1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Encephalomyelitis in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Encephalomyelitis: A general term indicating inflammation of the BRAIN and SPINAL CORD, often used to indicate an infectious process, but also applicable to a variety of autoimmune and toxic-metabolic conditions. There is significant overlap regarding the usage of this term and ENCEPHALITIS in the literature.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although Fasudil, a ROCK inhibitor, effectively suppressed encephalomyelitis (EAE), certain side effects may limit its clinical use." | 3.81 | FSD-C10: A more promising novel ROCK inhibitor than Fasudil for treatment of CNS autoimmunity. ( Chai, Z; Feng, L; Jiang, WJ; Li, YH; Liu, CY; Ma, CG; Wang, Q; Xiao, BG; Xin, YL; Yang, WF; Yang, XW; Yu, JZ; Zhang, GX, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xin, YL | 1 |
| Yu, JZ | 1 |
| Yang, XW | 1 |
| Liu, CY | 1 |
| Li, YH | 1 |
| Feng, L | 1 |
| Chai, Z | 1 |
| Yang, WF | 1 |
| Wang, Q | 1 |
| Jiang, WJ | 1 |
| Zhang, GX | 1 |
| Xiao, BG | 1 |
| Ma, CG | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Encephalomyelitis
| Article | Year |
|---|---|
FSD-C10: A more promising novel ROCK inhibitor than Fasudil for treatment of CNS autoimmunity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Autoimmunity; Cell Survival; Cells, Cultured | 2015 |