1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Diabetes, Gestational in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Diabetes, Gestational: Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the effects of fasudil on insulin resistance (IR) in HTR-8/SVneo cells." | 8.02 | Fasudil alleviated insulin resistance through promotion of proliferation, attenuation of cell apoptosis and inflammation and regulation of RhoA/Rho kinase/insulin/nuclear factor-κB signalling pathway in HTR-8/SVneo cells. ( Bai, Y; Du, Q; Du, R; Li, L; Li, P; Tang, L; Zhang, L; Zhang, W, 2021) |
| "The aim of this study was to evaluate the effects of fasudil on insulin resistance (IR) in HTR-8/SVneo cells." | 4.02 | Fasudil alleviated insulin resistance through promotion of proliferation, attenuation of cell apoptosis and inflammation and regulation of RhoA/Rho kinase/insulin/nuclear factor-κB signalling pathway in HTR-8/SVneo cells. ( Bai, Y; Du, Q; Du, R; Li, L; Li, P; Tang, L; Zhang, L; Zhang, W, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, Y | 1 |
| Du, Q | 1 |
| Zhang, L | 1 |
| Li, L | 2 |
| Tang, L | 1 |
| Zhang, W | 1 |
| Du, R | 1 |
| Li, P | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Diabetes, Gestational
| Article | Year |
|---|---|
Fasudil alleviated insulin resistance through promotion of proliferation, attenuation of cell apoptosis and inflammation and regulation of RhoA/Rho kinase/insulin/nuclear factor-κB signalling pathway in HTR-8/SVneo cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; | 2021 |