1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Dementia Praecox studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Research Excerpts

Excerpt	Relevance	Reference
"Current antipsychotics used to treat schizophrenia have associated problems, including serious side effects and treatment resistance."	5.72	Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia. ( Kaibuchi, K; Liao, J; Liu, Y; Miyagawa, Y; Mizoguchi, H; Nagai, T; Ozaki, N; Sawahata, M; Sobue, A; Takase, S; Tanaka, R; Yamada, K, 2022)
"Current antipsychotics used to treat schizophrenia have associated problems, including serious side effects and treatment resistance."	1.72	Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia. ( Kaibuchi, K; Liao, J; Liu, Y; Miyagawa, Y; Mizoguchi, H; Nagai, T; Ozaki, N; Sawahata, M; Sobue, A; Takase, S; Tanaka, R; Yamada, K, 2022)

Research

Studies (1)

Authors

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Dementia Praecox

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (100.00)	2.80

Authors	Studies
Takase, S	1
Liao, J	1
Liu, Y	1
Tanaka, R	1
Miyagawa, Y	1
Sawahata, M	1
Sobue, A	1
Mizoguchi, H	1
Nagai, T	1
Kaibuchi, K	1
Ozaki, N	1
Yamada, K	1