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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Degenerative Diseases, Central Nervous System

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Degenerative Diseases, Central Nervous System in 2 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Research Excerpts

ExcerptRelevanceReference
"Fasudil is a Rho kinase inhibitor and has been reported to have neuroprotective effects."1.39Rho kinase inhibitor fasudil protects against β-amyloid-induced hippocampal neurodegeneration in rats. ( Chen, X; Gao, W; Song, Y; Wang, LY; Zhu, MJ, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Killick, R1
Elliott, C1
Ribe, E1
Broadstock, M1
Ballard, C1
Aarsland, D1
Williams, G1
Song, Y1
Chen, X1
Wang, LY1
Gao, W1
Zhu, MJ1

Reviews

1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Degenerative Diseases, Central Nervous System

ArticleYear
Neurodegenerative Disease Associated Pathways in the Brains of Triple Transgenic Alzheimer's Model Mice Are Reversed Following Two Weeks of Peripheral Administration of Fasudil.
    International journal of molecular sciences, 2023, Jul-07, Volume: 24, Issue:13

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alzheimer Disease; Animals; Brain; Mice; Mice, Transg

2023

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Degenerative Diseases, Central Nervous System

ArticleYear
Rho kinase inhibitor fasudil protects against β-amyloid-induced hippocampal neurodegeneration in rats.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amyloid beta-Peptides; Animals; Hippocampus; Male; Ne

2013