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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Coronary Heart Disease

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Coronary Heart Disease in 4 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimokawa, H1
Morishige, K1
Miyata, K1
Kandabashi, T1
Eto, Y1
Ikegaki, I1
Asano, T1
Kaibuchi, K1
Takeshita, A1
Sargent, CA1
Sleph, PG1
Dzwonczyk, S1
Smith, MA1
Grover, GJ1
Knowlton, AA1
Eberli, FR1
Brecher, P1
Romo, GM1
Owen, A1
Apstein, CS1
Sonoki, H1
Uchida, Y1
Tomaru, T1
Sugimoto, T1

Other Studies

4 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Coronary Heart Disease

ArticleYear
Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo.
    Cardiovascular research, 2001, Volume: 51, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Blotting, Western; Cor

2001
Effect of calmodulin and protein kinase C inhibitors on globally ischemic rat hearts.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Animals; Benzimidazo

1992
A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Coronary Disease; Erythro

1991
[The role of protein kinase C in left ventricular relaxation impaired by global ischemia].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Coronary Disease; Dogs; Isoquinolin

1989