1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Coronary Disease in 4 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimokawa, H | 1 |
| Morishige, K | 1 |
| Miyata, K | 1 |
| Kandabashi, T | 1 |
| Eto, Y | 1 |
| Ikegaki, I | 1 |
| Asano, T | 1 |
| Kaibuchi, K | 1 |
| Takeshita, A | 1 |
| Sargent, CA | 1 |
| Sleph, PG | 1 |
| Dzwonczyk, S | 1 |
| Smith, MA | 1 |
| Grover, GJ | 1 |
| Knowlton, AA | 1 |
| Eberli, FR | 1 |
| Brecher, P | 1 |
| Romo, GM | 1 |
| Owen, A | 1 |
| Apstein, CS | 1 |
| Sonoki, H | 1 |
| Uchida, Y | 1 |
| Tomaru, T | 1 |
| Sugimoto, T | 1 |
4 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Coronary Disease
| Article | Year |
|---|---|
Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Blotting, Western; Cor | 2001 |
Effect of calmodulin and protein kinase C inhibitors on globally ischemic rat hearts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Animals; Benzimidazo | 1992 |
A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Coronary Disease; Erythro | 1991 |
[The role of protein kinase C in left ventricular relaxation impaired by global ischemia].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Coronary Disease; Dogs; Isoquinolin | 1989 |