1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Corneal Neovascularization in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Corneal Neovascularization: New blood vessels originating from the corneal blood vessels and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects and mechanisms of fasudil hydrochloride (fasudil) on and in alkali burn-induced corneal neovascularization (CNV) in mice." | 7.81 | Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice. ( Chen, RX; He, H; Li, P; Lin, LM; Pi, RB; Zeng, P; Zhou, SY, 2015) |
| "To investigate the effects and mechanisms of fasudil hydrochloride (fasudil) on and in alkali burn-induced corneal neovascularization (CNV) in mice." | 3.81 | Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice. ( Chen, RX; He, H; Li, P; Lin, LM; Pi, RB; Zeng, P; Zhou, SY, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeng, P | 1 |
| Pi, RB | 1 |
| Li, P | 1 |
| Chen, RX | 1 |
| Lin, LM | 1 |
| He, H | 1 |
| Zhou, SY | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Corneal Neovascularization
| Article | Year |
|---|---|
Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkalies; Animals; Burns, Chemical; Corneal Neovascul | 2015 |