1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Colonic Neoplasms in 11 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Poisson, L | 1 |
| Lopez-Charcas, O | 1 |
| Chadet, S | 1 |
| Bon, E | 1 |
| Lemoine, R | 1 |
| Brisson, L | 1 |
| Ouaissi, M | 1 |
| Baron, C | 1 |
| Besson, P | 1 |
| Roger, S | 1 |
| Moussata, D | 1 |
| Liu, Z | 1 |
| Zou, D | 1 |
| Yang, X | 1 |
| Xue, X | 1 |
| Zuo, L | 1 |
| Zhou, Q | 1 |
| Hu, R | 1 |
| Wang, Y | 1 |
| Hakomori, S | 1 |
| Marchetti, C | 1 |
| Migliorati, G | 1 |
| Moraca, R | 1 |
| Riccardi, C | 1 |
| Nicoletti, I | 1 |
| Fabiani, R | 1 |
| Mastrandrea, V | 1 |
| Morozzi, G | 1 |
| Cafferata, EG | 1 |
| González-Guerrico, AM | 1 |
| Giordano, L | 1 |
| Pivetta, OH | 1 |
| Santa-Coloma, TA | 1 |
| Fournès, B | 1 |
| Sadekova, S | 1 |
| Turbide, C | 1 |
| Létourneau, S | 1 |
| Beauchemin, N | 1 |
| Keller, K | 1 |
| Olivier, M | 1 |
| Chadee, K | 1 |
| Bargon, J | 1 |
| Trapnell, BC | 1 |
| Yoshimura, K | 1 |
| Dalemans, W | 1 |
| Pavirani, A | 1 |
| Lecocq, JP | 1 |
| Crystal, RG | 1 |
| Chakrabarty, S | 1 |
| Matsubara, N | 1 |
| Fuchimoto, S | 1 |
| Orita, K | 1 |
| Turner, JT | 1 |
| Franklin, CC | 1 |
| Bollinger, DW | 1 |
| Kim, HD | 1 |
11 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Colonic Neoplasms
| Article | Year |
|---|---|
Rock inhibition promotes Na
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Cell Line, Tumor; Cell Movement; Colonic Neop | 2020 |
Melatonin inhibits colon cancer RKO cell migration by downregulating Rho‑associated protein kinase expression via the p38/MAPK signaling pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2017 |
Novel endothelial cell activation factor(s) released from activated platelets which induce E-selectin expression and tumor cell adhesion to endothelial cells: a preliminary note.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Factors; Cell Adhesion | 1994 |
Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Butyrates; Butyric Acid; Calcium; Chelatin | 1997 |
Interleukin-1beta regulates CFTR expression in human intestinal T84 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Benzoquinones; Cell Line; Colon; Colo | 2000 |
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antigens, CD; Antigens, | 2001 |
The fast release of mucin secretion from human colonic cells induced by Entamoeba histolytica is dependent on contact and protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Alkaloids; Animals; Calcium; Carbohyd | 1992 |
Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Cell Line; Colonic Neoplasms; Cystic Fibr | 1992 |
Role of protein kinase C in transforming growth factor-beta 1 induction of carcinoembryonic antigen in human colon carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoembryonic Antigen; Colonic Neoplasms; Humans; | 1992 |
Differing roles of protein kinase C on the antiproliferative effects of tumor necrosis factor alpha and beta on LoVo cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Colonic Neoplasms; Dose-Response Relationship, Drug; | 1990 |
Vasoactive intestinal peptide stimulates active K+ transport and Na(+)-K(+)-Cl- cotransport in HT-29 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Amiloride; Biological Transport; Bume | 1990 |