1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Charcot-Marie-Tooth Disease in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Charcot-Marie-Tooth Disease: A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanwal, S | 1 |
| Perveen, S | 1 |
| Nobbio, L | 1 |
| Sturla, L | 1 |
| Fiorese, F | 1 |
| Usai, C | 1 |
| Basile, G | 1 |
| Moreschi, I | 1 |
| Benvenuto, F | 1 |
| Zocchi, E | 1 |
| De Flora, A | 1 |
| Schenone, A | 1 |
| Bruzzone, S | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Charcot-Marie-Tooth Disease
| Article | Year |
|---|---|
In-silico and Molecular Analysis of Reticulon 4asNovel therapeutic option for axonal regeneration.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Axons; Charcot-Marie-Tooth Disease; Child, Pre | 2019 |
P2X7-mediated increased intracellular calcium causes functional derangement in Schwann cells from rats with CMT1A neuropathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Genetically Modified; Blotting, Wes | 2009 |