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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Central Nervous System Neoplasms

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Central Nervous System Neoplasms in 1 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Central Nervous System Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.

Research Excerpts

ExcerptRelevanceReference
"The phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has not been established."1.42Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. ( Akers, AL; Austin, C; Awad, IA; De Souza, JM; Gallione, CJ; Gunel, M; Lee, C; Marchuk, DA; McDonald, DA; Mikati, AG; Min, W; Rebeiz, T; Rorrer, A; Shenkar, R; Shi, C; Stockton, RA; Zhang, L, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shenkar, R1
Shi, C1
Rebeiz, T1
Stockton, RA1
McDonald, DA1
Mikati, AG1
Zhang, L1
Austin, C1
Akers, AL1
Gallione, CJ1
Rorrer, A1
Gunel, M1
Min, W1
De Souza, JM1
Lee, C1
Marchuk, DA1
Awad, IA1

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Central Nervous System Neoplasms

ArticleYear
Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.
    Genetics in medicine : official journal of the American College of Medical Genetics, 2015, Volume: 17, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Adult; Animals; Apoptosis Regulatory Prot

2015