1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Cataract, Membranous in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effects of two serine-threonine protein kinase inhibitors in a mouse lens culture system previously designed to investigate cortical cataracts caused by L-buthionine sulfoximine (BSO), inhibitor of GSH biosynthesis." | 3.72 | Induction of cortical cataracts in cultured mouse lenses with H-89, an inhibitor of protein kinase A. ( Banerjee, U; Calvin, HI; Fu, SC; Guo, L; Li, W; Wu, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, B | 1 |
| Heatley, GA | 1 |
| Filla, MS | 1 |
| Kaufman, PL | 1 |
| Calvin, HI | 1 |
| Wu, K | 1 |
| Li, W | 1 |
| Guo, L | 1 |
| Banerjee, U | 1 |
| Fu, SC | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Cataract, Membranous
| Article | Year |
|---|---|
Effect of H-7 on secondary cataract after phacoemulsification in the live rabbit eye.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actomyosin; Animals; Cataract; Dose-Response Relation | 2010 |
Induction of cortical cataracts in cultured mouse lenses with H-89, an inhibitor of protein kinase A.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Crystallin A Chain; Animals; Animals, Newborn; | 2003 |