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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Carotid Arteriopathies, Traumatic

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Carotid Arteriopathies, Traumatic in 1 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Research Excerpts

ExcerptRelevanceReference
"Fasudil is an inhibitor of protein kinases, including myosin light chain kinase and Rho associated kinase, thereby inhibiting myosin phosphorylation, and it has been clinically used to prevent vasospasm following subarachnoid hemorrage."5.30The kinase inhibitor fasudil (HA-1077) reduces intimal hyperplasia through inhibiting migration and enhancing cell loss of vascular smooth muscle cells. ( Fukui, R; Hoshiga, M; Ii, M; Ishihara, T; Kohbayashi, E; Nakakoji, T; Negoro, N; Nishiguchi, F; Ohsawa, N; Sasaki, Y; Seto, M; Shibata, N, 1999)
"Fasudil is an inhibitor of protein kinases, including myosin light chain kinase and Rho associated kinase, thereby inhibiting myosin phosphorylation, and it has been clinically used to prevent vasospasm following subarachnoid hemorrage."1.30The kinase inhibitor fasudil (HA-1077) reduces intimal hyperplasia through inhibiting migration and enhancing cell loss of vascular smooth muscle cells. ( Fukui, R; Hoshiga, M; Ii, M; Ishihara, T; Kohbayashi, E; Nakakoji, T; Negoro, N; Nishiguchi, F; Ohsawa, N; Sasaki, Y; Seto, M; Shibata, N, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Negoro, N1
Hoshiga, M1
Seto, M1
Kohbayashi, E1
Ii, M1
Fukui, R1
Shibata, N1
Nakakoji, T1
Nishiguchi, F1
Sasaki, Y1
Ishihara, T1
Ohsawa, N1

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Carotid Arteriopathies, Traumatic

ArticleYear
The kinase inhibitor fasudil (HA-1077) reduces intimal hyperplasia through inhibiting migration and enhancing cell loss of vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1999, Aug-19, Volume: 262, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Actins; Animals; Aorta; Carotid A

1999