1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Carcinoma, Squamous Cell in 6 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral squamous cell carcinoma (OSCC) is the most malignant lesion occurring in the head and neck." | 1.42 | HA-1077 inhibits cell migration/invasion of oral squamous cell carcinoma. ( Crema, VO; Moreira Carboni, Sde S; Pinheiro, NM; Rodrigues Lima, NA; Tavares-Murta, BM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyamoto, C | 1 |
| Maehata, Y | 1 |
| Motohashi, K | 1 |
| Ozawa, S | 1 |
| Ikoma, T | 1 |
| Hidaka, K | 1 |
| Wada-Takahashi, S | 1 |
| Takahashi, SS | 1 |
| Yoshino, F | 1 |
| Yoshida, A | 1 |
| Kubota, E | 1 |
| Hata, R | 1 |
| Lee, MC | 1 |
| Moreira Carboni, Sde S | 1 |
| Rodrigues Lima, NA | 1 |
| Pinheiro, NM | 1 |
| Tavares-Murta, BM | 1 |
| Crema, VO | 1 |
| Tsai, CH | 1 |
| Hsieh, YS | 1 |
| Yang, SF | 1 |
| Chou, MY | 1 |
| Chang, YC | 1 |
| Hosoi, K | 1 |
| Shioda, Y | 1 |
| Ueha, T | 1 |
| Atsumi, T | 1 |
| Sugita, K | 1 |
| Kurihara, K | 1 |
| Kitajima, Y | 2 |
| Owaribe, K | 1 |
| Nishizawa, Y | 1 |
| Jokura, Y | 1 |
| Yaoita, H | 2 |
| Inoue, S | 1 |
| Nagao, S | 1 |
| Nagata, K | 1 |
| Nozawa, Y | 1 |
6 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Fasudil, a Rho kinase inhibitor, suppresses tumor growth by inducing CXCL14/BRAK in head and neck squamous cell carcinoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2014 |
HA-1077 inhibits cell migration/invasion of oral squamous cell carcinoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Antineoplastic Agents; Carcinoma, | 2015 |
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Squamous Cell; Cell Culture Techniques; Do | 2003 |
ATP- and EGF-stimulated phosphatidulinositol synthesis by two different pathways, phospholipase D and diacylglycerol kinase, in A-431 epidermoid carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Bradykinin; Calcimycin; Calci | 1996 |
Phorbol ester- and calcium-induced reorganization of 180-kDa bullous pemphigoid antigen on the ventral surface of cultured human keratinocytes as studied by immunofluorescence and immunoelectron microscopy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Autoantigens; Calcium; Carcinoma, Squamous Cell; Carr | 1992 |
Biphasic effects of 12-O-tetradecanoylphorbol-13-acetate on the cell morphology of low calcium-grown human epidermal carcinoma cells: involvement of translocation and down regulation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium Channel Blockers; Carcinoma, Squamou | 1988 |