1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Carcinoma, Ductal, Pancreatic in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The high mortality of pancreatic cancer demands that new therapeutic avenues be developed." | 1.48 | Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth. ( Cutiongco, MF; Gadegaard, N; Jagiełło, A; Kamphorst, JJ; Mackay, G; McGarry, L; Michalopoulou, E; Munro, J; Olson, MF; Pajic, M; Rath, N; Sumpton, D; Timpson, P; Unbekandt, M; Vennin, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hosein, AN | 1 |
| Brekken, RA | 1 |
| Maitra, A | 1 |
| Rath, N | 1 |
| Munro, J | 1 |
| Cutiongco, MF | 1 |
| Jagiełło, A | 1 |
| Gadegaard, N | 1 |
| McGarry, L | 1 |
| Unbekandt, M | 1 |
| Michalopoulou, E | 1 |
| Kamphorst, JJ | 1 |
| Sumpton, D | 1 |
| Mackay, G | 1 |
| Vennin, C | 1 |
| Pajic, M | 1 |
| Timpson, P | 1 |
| Olson, MF | 1 |
1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Carcinoma, Ductal, Pancreatic
| Article | Year |
|---|---|
Pancreatic cancer stroma: an update on therapeutic targeting strategies.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiogenesis Inhibitors; Animals; Antineoplastic Agen | 2020 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Carcinoma, Ductal, Pancreatic
| Article | Year |
|---|---|
Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Hydroxyphenethylamine; Amides; Animals; Antineoplas | 2018 |