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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Cancer of Prostate

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Cancer of Prostate in 5 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Research Excerpts

ExcerptRelevanceReference
"Human prostate cancer cell lines PC3 and DU145 were treated with fasudil at the concentrations of 5, 10, 20, 40, 80, and 160 μmol/L, respectively, and those as negative controls cultured in the Ham's-F12 medium, all for 24 hours."1.43[Effects of the Rho-kinase inhibitor fasudil on the invasion, migration, and apoptosis of human prostate cancer PC3 and DU145 cells]. ( Chen, H; Chen, Y; Dai, YT; Gao, QQ; Han, YF; Xu, ZP; Yu, W; Zhu, LL, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, QQ1
Chen, H1
Chen, Y1
Xu, ZP1
Zhu, LL1
Yu, W1
Han, YF1
Dai, YT1
Chen, W1
Mao, K1
Hua-Huy, T1
Bei, Y1
Liu, Z1
Dinh-Xuan, AT1
Tang, AT1
Campbell, WB1
Nithipatikom, K1
Lee, YJ1
Berns, CM1
Erdos, G1
Corry, PM1
Chang, NS1

Other Studies

5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Cancer of Prostate

ArticleYear
[Effects of the Rho-kinase inhibitor fasudil on the invasion, migration, and apoptosis of human prostate cancer PC3 and DU145 cells].
    Zhonghua nan ke xue = National journal of andrology, 2016, Volume: 22, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Prol

2016
Fasudil inhibits prostate cancer-induced angiogenesis in vitro.
    Oncology reports, 2014, Volume: 32, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line, Tumor; Cell Movement; Cell Proliferation;

2014
ROCK1 feedback regulation of the upstream small GTPase RhoA.
    Cellular signalling, 2012, Volume: 24, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; ADP Ribose Transferases; Amides;

2012
Effect of isoquinolinesulfonamides on heat shock gene expression during heating at 41 degrees C in human carcinoma cell lines.
    Biochemical and biophysical research communications, 1994, Mar-15, Volume: 199, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Northern; Breast Neoplasms; Cyclic AMP-Depe

1994
Hyaluronidase enhancement of TNF-mediated cell death is reversed by TGF-beta 1.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases

1997