1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Cancer of Ovary in 6 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The poor prognosis of advanced ovarian cancer comes from increased invasiveness of human ovarian cancer cells." | 1.35 | Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells. ( Hashimoto, K; Kawase, C; Kimura, T; Mabuchi, S; Morishige, K; Ogata, S; Ooyagi, C; Sakata, M; Sawada, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogata, S | 1 |
| Morishige, K | 1 |
| Sawada, K | 1 |
| Hashimoto, K | 1 |
| Mabuchi, S | 1 |
| Kawase, C | 1 |
| Ooyagi, C | 1 |
| Sakata, M | 1 |
| Kimura, T | 1 |
| Ohta, T | 1 |
| Takahashi, T | 1 |
| Shibuya, T | 1 |
| Amita, M | 1 |
| Henmi, N | 1 |
| Takahashi, K | 1 |
| Kurachi, H | 1 |
| Obata, NH | 1 |
| Okazaki, K | 1 |
| Maeda, O | 1 |
| Kikkawa, F | 1 |
| Tomoda, Y | 1 |
| Hidaka, H | 1 |
| Powell, CB | 1 |
| Manning, K | 1 |
| Collins, JL | 1 |
| Gimond, C | 1 |
| Mercier, I | 1 |
| Weber, I | 1 |
| Aumailley, M | 1 |
| Hayakawa, A | 1 |
| Yokoyama, I | 1 |
| Tajiri, H | 1 |
| Okamoto, T | 1 |
| Nakashima, I | 1 |
6 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Cancer of Ovary
| Article | Year |
|---|---|
Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Carcinoma; Cell Movem | 2009 |
Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line, Tumor; Cisplatin; Drug Synergism; Female; | 2012 |
Effect of KN-62, Ca2+/calmodulin-dependent protein kinase II inhibitor, on adriamycin resistance of human ovarian cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ATP Binding Cassette Transporter, Subfamily B, Member | 1995 |
Interferon-alpha (IFN alpha) induces a cytolytic mechanism in ovarian carcinoma cells through a protein kinase C-dependent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Cell Survival; Dacti | 1993 |
Adhesion complexes formed by OVCAR-4 cells on laminin 1 differ from those observed on fibronectin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Actins; Cell Adhesion; Enzyme Inh | 1996 |
Protein kinase C-dependent anti-apoptotic mechanism that is associated with high sensitivity to anti-Fas antibody in ovarian cancer cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Apoptosis; Calcimycin; Cell Division; Cer | 1999 |