1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Burkitt Lymphoma in 6 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Burkitt Lymphoma: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horie, K | 1 |
| Ohashi, M | 1 |
| Satoh, Y | 1 |
| Sairenji, T | 1 |
| Faris, M | 1 |
| Gaskin, F | 1 |
| Parsons, JT | 1 |
| Fu, SM | 1 |
| Adachi, S | 1 |
| Kubota, M | 1 |
| Lin, YW | 1 |
| Okuda, A | 1 |
| Matsubara, K | 1 |
| Wakazono, Y | 1 |
| Hirota, H | 1 |
| Kuwakado, K | 1 |
| Akiyama, Y | 1 |
| Findik, D | 1 |
| Song, Q | 1 |
| Hidaka, H | 1 |
| Lavin, M | 1 |
| Duraj, J | 1 |
| Kovacikova, M | 1 |
| Sedlak, J | 1 |
| Koppel, J | 1 |
| Sobel, A | 1 |
| Chorvath, B | 1 |
| Lazdins, J | 1 |
| Zompetta, C | 1 |
| Grimaldi, S | 1 |
| Barile, G | 1 |
| Venanzoni, M | 1 |
| Frati, L | 1 |
| Faggioni, A | 1 |
1 trial available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Burkitt Lymphoma
| Article | Year |
|---|---|
In vivo administration of granulocyte colony-stimulating factor promotes neutrophil survival in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Burkitt Lymphoma; Cell Survival; Child; C | 1994 |
5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Burkitt Lymphoma
| Article | Year |
|---|---|
The role of p38 mitogen-activated protein kinase in regulating interleukin-10 gene expression in Burkitt's lymphoma cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Burkitt Lymphoma; Cell Line; Enzyme Inhibitors; Gene | 2007 |
CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antigens, CD; Antigens, Diffe | 1994 |
Protein kinase A inhibitors enhance radiation-induced apoptosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Burkitt Lymphoma; Cyclic AMP-Dependent Pro | 1995 |
The protein kinase C inhibitor H7 blocks phosphorylation of stathmin during TPA-induced growth inhibition of human pre-B leukemia REH6 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Burkitt Lymphoma; Calmodulin; Cell Cycle; Cell Divisi | 1995 |
TPA induction of Epstein-Barr virus early antigens in Raji cells is blocked by selective protein kinase-C inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Neoplasm; Antigens, Viral; Burkitt Lymphoma | 1987 |