1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Brain Damage, Chronic in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pharmacological treatment for cerebral ischemia cannot attain sufficiently high concentrations of the drugs in the cerebrospinal fluid (CSF) without precipitating systemic side effects." | 1.31 | Neuroprotection by intrathecal application of liposome-entrapped fasudil in a rat model of ischemia. ( Allen, TM; Ishida, T; Kirchmeier, MJ; Shuaib, A; Takanashi, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takanashi, Y | 1 |
| Ishida, T | 1 |
| Kirchmeier, MJ | 1 |
| Shuaib, A | 1 |
| Allen, TM | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Brain Damage, Chronic
| Article | Year |
|---|---|
Neuroprotection by intrathecal application of liposome-entrapped fasudil in a rat model of ischemia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain Damage, Chronic; Brain Ischemia; Cereb | 2001 |