1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Bone Loss, Osteoclastic in 3 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ang, ES | 1 |
| Zhang, P | 1 |
| Steer, JH | 1 |
| Tan, JW | 1 |
| Yip, K | 1 |
| Zheng, MH | 2 |
| Joyce, DA | 1 |
| Xu, J | 1 |
| Kukita, T | 1 |
| Kukita, A | 1 |
| Hata, K | 1 |
| Kurisu, K | 1 |
| Wood, DJ | 1 |
| Papadimitriou, JM | 1 |
| Nicholson, GC | 1 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Calcium/calmodulin-dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Bone Resorption; Calcium Signa | 2007 |
12-O-tetradecanoylphorbol-13-acetate inhibits osteoclast-like cell differentiation in rat bone marrow cultures by inducing macrophage polykaryons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acid Phosphatase; Animals; Biomarkers; Bone Marrow; B | 1992 |
Evidence that protein kinase-A, calcium-calmodulin kinase and cytoskeletal proteins are involved in osteoclast retraction induced by calcitonin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Resorption; Calcitonin; Cells, Cultured | 1992 |