1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Bone Cancer in 5 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of human MG-63 osteosarcoma cells with human recombinant transforming growth factor beta 1 (TGF-beta 1) was found to inhibit cell proliferation." | 7.69 | Effects of transforming growth factor beta 1 on the regulation of osteocalcin synthesis in human MG-63 osteosarcoma cells. ( Jääskeläinen, T; Mäenpää, PH; Pirskanen, A, 1994) |
| "Treatment of human MG-63 osteosarcoma cells with human recombinant transforming growth factor beta 1 (TGF-beta 1) was found to inhibit cell proliferation." | 3.69 | Effects of transforming growth factor beta 1 on the regulation of osteocalcin synthesis in human MG-63 osteosarcoma cells. ( Jääskeläinen, T; Mäenpää, PH; Pirskanen, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, Y | 1 |
| Cai, X | 1 |
| Fan, J | 1 |
| Zhang, L | 1 |
| Li, Z | 1 |
| Ren, J | 1 |
| Wu, G | 1 |
| Zhu, F | 1 |
| Pirskanen, A | 1 |
| Jääskeläinen, T | 1 |
| Mäenpää, PH | 1 |
| Arao, M | 1 |
| Yamaguchi, T | 1 |
| Sugimoto, T | 1 |
| Fukase, M | 1 |
| Chihara, K | 1 |
| Broberg, A | 1 |
| Nissinen, L | 1 |
| Potila, M | 1 |
| Heino, J | 1 |
| Miñana, MD | 1 |
| Felipo, V | 1 |
| Cortés, F | 1 |
| Grisolía, S | 1 |
5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Bone Cancer
| Article | Year |
|---|---|
RhoA/ROCK pathway inhibition by fasudil suppresses the vasculogenic mimicry of U2OS osteosarcoma cells in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell | 2017 |
Effects of transforming growth factor beta 1 on the regulation of osteocalcin synthesis in human MG-63 osteosarcoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Base Sequence; Bone Neoplasms; Calcitriol; Cell Divis | 1994 |
Protein kinase C is crucial for the stimulation of sodium-dependent phosphate transport by parathyroid hormone-related peptide in osteoblast-like cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Biological Transport; Bon | 1994 |
Three-dimensional collagen regulates collagen gene expression by a mechanism that requires serine/threonine kinases and is independent of mechanical contraction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, CD; Bone Neoplasms; Cell Adhesion; Collagen | 2001 |
Inhibition of protein kinase C arrests proliferation of human tumors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Ce | 1991 |