1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Body Weight in 8 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)." | 7.77 | Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011) |
| " In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)." | 3.77 | Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, LA | 1 |
| Darwish, HA | 1 |
| Abdelsalam, RM | 1 |
| Amin, HA | 1 |
| García-Rojo, G | 1 |
| Fresno, C | 1 |
| Vilches, N | 1 |
| Díaz-Véliz, G | 1 |
| Mora, S | 1 |
| Aguayo, F | 1 |
| Pacheco, A | 1 |
| Parra-Fiedler, N | 1 |
| Parra, CS | 1 |
| Rojas, PS | 1 |
| Tejos, M | 1 |
| Aliaga, E | 1 |
| Fiedler, JL | 1 |
| Ziino, AJ | 1 |
| Ivanovska, J | 1 |
| Belcastro, R | 1 |
| Kantores, C | 1 |
| Xu, EZ | 1 |
| Lau, M | 1 |
| McNamara, PJ | 1 |
| Tanswell, AK | 1 |
| Jankov, RP | 1 |
| Zoer, B | 1 |
| Blanco, CE | 1 |
| Villamor, E | 1 |
| Guo, P | 1 |
| Wu, C | 1 |
| Masaki, T | 1 |
| Mori, H | 1 |
| Nishiyama, A | 1 |
| Guan, SJ | 1 |
| Ma, ZH | 1 |
| Wu, YL | 1 |
| Zhang, JP | 1 |
| Liang, F | 1 |
| Weiss, JW | 1 |
| Guo, QY | 1 |
| Wang, JY | 1 |
| Ji, ES | 1 |
| Chu, L | 1 |
| Kanazawa, Y | 1 |
| Takahashi-Fujigasaki, J | 1 |
| Ishizawa, S | 1 |
| Takabayashi, N | 1 |
| Ishibashi, K | 1 |
| Matoba, K | 1 |
| Kawanami, D | 1 |
| Yokota, T | 1 |
| Tajima, N | 1 |
| Utsunomiya, K | 1 |
| Watanabe, T | 1 |
| Okawa, S | 1 |
| Itoga, H | 1 |
| Imanaka, T | 1 |
| Suga, T | 1 |
8 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Body Weight
| Article | Year |
|---|---|
Role of Rho Kinase Inhibition in the Protective Effect of Fasudil and Simvastatin Against 3-Nitropropionic Acid-Induced Striatal Neurodegeneration and Mitochondrial Dysfunction in Rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; bcl-2-Associated X Protein; Behavior, Animal | 2016 |
The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Depolymerizing Factors; Animals; Body Weight; D | 2017 |
Effects of rho-kinase inhibition on pulmonary hypertension, lung growth, and structure in neonatal rats chronically exposed to hypoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Airway Remodeling; Amides; Animals; Animals, Newborn; | 2010 |
Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13 | 2010 |
Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Antihypertensive Agents; Biomar | 2011 |
Long-term administration of fasudil improves cardiomyopathy in streptozotocin-induced diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin-Converting Enzyme Inhibitors; Animals; An | 2012 |
The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; beta Catenin; Body Weight; Cadherins; Cateni | 2013 |
Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by hypolipidemic peroxisome proliferators.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bezafibrate; Body Weight; Calmodulin; Catala | 1992 |