1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Blood Pressure, High in 42 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
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" In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)." | 7.77 | Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011) |
"These results suggest that fasudil has beneficial effects on retinal vascular complications associated with chronic hypertension." | 7.74 | Vasodilator effects of fasudil, a Rho-kinase inhibitor, on retinal arterioles in stroke-prone spontaneously hypertensive rats. ( Ishii, K; Kametaka, S; Mori, A; Nakahara, T; Okamura, N; Saito, M; Sakamoto, K, 2007) |
" A selective Rho-kinase inhibitor, fasudil, has recently been shown to improve renal damage resulting from hypertensive glomerulosclerosis, unilateral ureteral obstruction (for interstitial renal fibrosis) and subtotal nephrectomy." | 4.83 | Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury. ( Hayashi, K; Homma, K; Kanda, T; Saruta, T; Sugano, N; Wakino, S, 2006) |
"Twenty 12-week-old healthy male Sprague-Dawley rats were randomly divided into groups A (control), B (hypertension) and C (fasudil treatment)." | 3.78 | [Fasudil improves erectile function of hypertensive rats]. ( Chen, F; Cheng, Y; Jiang, R; Ma, ZP; Yang, HF, 2012) |
" In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)." | 3.77 | Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011) |
"These results suggest that fasudil has beneficial effects on retinal vascular complications associated with chronic hypertension." | 3.74 | Vasodilator effects of fasudil, a Rho-kinase inhibitor, on retinal arterioles in stroke-prone spontaneously hypertensive rats. ( Ishii, K; Kametaka, S; Mori, A; Nakahara, T; Okamura, N; Saito, M; Sakamoto, K, 2007) |
"To determine the effects of fasudil, a Rho-kinase inhibitor, on mineralocorticoid-induced myocardial remodeling, we investigated whether fasudil would suppress myocardial fibrosis and inflammation in deoxycorticosterone-acetate (DOCA)/salt hypertensive rats." | 3.74 | Fasudil attenuates myocardial fibrosis in association with inhibition of monocyte/macrophage infiltration in the heart of DOCA/salt hypertensive rats. ( Inoue, H; Ishimaru, K; Kagitani, S; Takabayashi, D; Takata, M; Ueno, H, 2007) |
"We investigated the effects of fasudil, a Rho kinase inhibitor, on hypertension in spontaneously hypertensive rats and on the catecholamine synthetic pathway." | 3.74 | Fasudil attenuates sympathetic nervous activity in the adrenal medulla of spontaneously hypertensive rats. ( Hayashi, M; Kobayashi, S; Kumai, T; Matsumoto, N; Nakaya, S; Takeba, Y; Tsuzuki, Y; Yanagida, Y, 2007) |
"Hypertensive cardiac hypertrophy is associated with reduced coronary flow reserve, but its impact on coronary flow regulation and vasomotor function remains incompletely understood and requires further investigation." | 1.46 | Enhanced endothelin-1/Rho-kinase signalling and coronary microvascular dysfunction in hypertensive myocardial hypertrophy. ( Hein, TW; Kuo, L; Lu, G; Ren, Y; Tsai, SH; Xu, X, 2017) |
"Fasudil treatment significantly ameliorated those DHF-related myocardial changes." | 1.35 | Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in hypertensive rats. ( Fukui, S; Fukumoto, Y; Kagaya, Y; Nawata, J; Saji, K; Shimokawa, H; Shinozaki, T; Suzuki, J; Tawara, S, 2008) |
" H-7 produced a shift to the right of the dose-response curve for the PKC activator, 12-o-tetradecanoylphorbol-13-acetate (TPA) in the case of SHR aortas, while no such shift was noted in tissues from WKY." | 1.28 | Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats. ( Iwasaki, T; Miyata, S; Morita, S; Nagai, K; Shibata, R, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (4.76) | 18.7374 |
1990's | 7 (16.67) | 18.2507 |
2000's | 19 (45.24) | 29.6817 |
2010's | 14 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Tsai, SH | 1 |
Lu, G | 1 |
Xu, X | 2 |
Ren, Y | 1 |
Hein, TW | 1 |
Kuo, L | 1 |
Chan, SL | 1 |
Cipolla, MJ | 1 |
Ocaranza, MP | 1 |
Fierro, C | 1 |
Jalil, JE | 1 |
Moya, J | 1 |
Gonzalez, L | 1 |
Molina, C | 1 |
Mancilla, C | 1 |
Vaněčková, I | 2 |
Behuliak, M | 2 |
Hojná, S | 1 |
Kopkan, L | 1 |
Kadlecová, M | 1 |
Zicha, J | 2 |
Yuan, TY | 1 |
Chen, D | 1 |
Chen, YC | 1 |
Zhang, HF | 1 |
Niu, ZR | 1 |
Jiao, XZ | 1 |
Xie, P | 1 |
Fang, LH | 1 |
Du, GH | 1 |
Snelder, N | 1 |
Ploeger, BA | 1 |
Luttringer, O | 1 |
Rigel, DF | 1 |
Fu, F | 1 |
Beil, M | 1 |
Stanski, DR | 1 |
Danhof, M | 1 |
Vavřínová, A | 1 |
Bencze, M | 1 |
Polgárová, K | 1 |
Ergang, P | 1 |
Kuneš, J | 1 |
Chan, CK | 1 |
Mak, JC | 1 |
Man, RY | 1 |
Vanhoutte, PM | 1 |
Ying, Z | 1 |
Yue, P | 1 |
Zhong, M | 1 |
Sun, Q | 1 |
Mikolaj, M | 1 |
Wang, A | 1 |
Brook, RD | 1 |
Chen, LC | 1 |
Rajagopalan, S | 1 |
Büssemaker, E | 1 |
Herbrig, K | 1 |
Pistrosch, F | 1 |
Palm, C | 1 |
Passauer, J | 1 |
de Frutos, S | 1 |
Caldwell, E | 1 |
Nitta, CH | 1 |
Kanagy, NL | 1 |
Wang, J | 1 |
Wang, W | 1 |
Walker, MK | 1 |
Gonzalez Bosc, LV | 1 |
Ray, P | 1 |
Wright, J | 1 |
Adam, J | 1 |
Boucharens, S | 1 |
Black, D | 1 |
Brown, AR | 1 |
Epemolu, O | 1 |
Fletcher, D | 1 |
Huggett, M | 1 |
Jones, P | 1 |
Laats, S | 1 |
Lyons, A | 1 |
de Man, J | 1 |
Morphy, R | 1 |
Sherborne, B | 1 |
Sherry, L | 1 |
Straten, Nv | 1 |
Westwood, P | 1 |
York, M | 1 |
Guo, P | 1 |
Wu, C | 1 |
Masaki, T | 1 |
Mori, H | 1 |
Nishiyama, A | 1 |
Ma, ZP | 1 |
Jiang, R | 1 |
Cheng, Y | 1 |
Yang, HF | 1 |
Chen, F | 1 |
Inoue, S | 1 |
Saito, M | 4 |
Takenaka, A | 2 |
Ohmasa, F | 2 |
Dimitriadis, F | 2 |
Tsounapi, P | 2 |
Sejima, T | 1 |
Shimizu, S | 2 |
Kinoshita, Y | 2 |
Satoh, K | 2 |
Kitatani, K | 1 |
Mukai, Y | 2 |
Higashi, M | 1 |
Shimokawa, H | 4 |
Hattori, T | 1 |
Hiroki, J | 1 |
Morikawa, K | 1 |
Ichiki, T | 1 |
Takahashi, S | 1 |
Takeshita, A | 2 |
Kanda, T | 3 |
Wakino, S | 3 |
Hayashi, K | 3 |
Homma, K | 3 |
Ozawa, Y | 1 |
Saruta, T | 3 |
Nakayama, M | 1 |
Amano, M | 1 |
Kawabata, S | 1 |
Kaibuchi, K | 1 |
Takefuji, M | 1 |
Jarajapu, YP | 1 |
Knot, HJ | 1 |
Yoshioka, K | 1 |
Tatematsu, S | 1 |
Hasegawa, K | 1 |
Takamatsu, I | 1 |
Sugano, N | 2 |
Nishikimi, T | 2 |
Matsuoka, H | 1 |
Chapados, R | 1 |
Abe, K | 1 |
Ihida-Stansbury, K | 1 |
McKean, D | 1 |
Gates, AT | 1 |
Kern, M | 1 |
Merklinger, S | 1 |
Elliott, J | 1 |
Plant, A | 1 |
Jones, PL | 1 |
Okamura, N | 1 |
Mori, A | 1 |
Sakamoto, K | 1 |
Kametaka, S | 1 |
Nakahara, T | 1 |
Ishii, K | 1 |
Ishimaru, K | 1 |
Ueno, H | 1 |
Kagitani, S | 1 |
Takabayashi, D | 1 |
Takata, M | 1 |
Inoue, H | 1 |
Kumai, T | 1 |
Takeba, Y | 1 |
Matsumoto, N | 1 |
Nakaya, S | 1 |
Tsuzuki, Y | 1 |
Yanagida, Y | 1 |
Hayashi, M | 1 |
Kobayashi, S | 1 |
Fukui, S | 1 |
Fukumoto, Y | 1 |
Suzuki, J | 1 |
Saji, K | 1 |
Nawata, J | 1 |
Tawara, S | 1 |
Shinozaki, T | 1 |
Kagaya, Y | 1 |
Neusser, M | 1 |
Tepel, M | 1 |
Golinski, P | 1 |
Zhu, Z | 1 |
Rahn, KH | 1 |
Spieker, C | 1 |
Zidek, W | 1 |
Nakane, H | 1 |
Yao, H | 1 |
Ibayashi, S | 1 |
Kitazono, T | 1 |
Ooboshi, H | 1 |
Uchimura, H | 1 |
Fujishima, M | 1 |
Chan, JY | 1 |
Chang, JW | 1 |
Chan, SH | 1 |
Masumoto, A | 1 |
Hirooka, Y | 1 |
Hironaga, K | 1 |
Setoguchi, S | 1 |
Kuriyama, S | 1 |
Nakamura, K | 1 |
Horiguchi, M | 1 |
Uchida, H | 1 |
Sakai, O | 1 |
Soloviev, AI | 1 |
Bershtein, SA | 1 |
Shibata, R | 1 |
Morita, S | 1 |
Nagai, K | 1 |
Miyata, S | 1 |
Iwasaki, T | 1 |
Hano, T | 1 |
Shiotani, M | 1 |
Baba, A | 1 |
Ura, M | 2 |
Nakamura, Y | 1 |
Tomobuchi, Y | 1 |
Nishio, I | 2 |
Masuyama, Y | 3 |
Tsuda, K | 2 |
Inariba, H | 1 |
Kanayama, Y | 1 |
Takaori, K | 1 |
Itoh, S | 1 |
Inoue, T | 1 |
Takeda, T | 1 |
Shima, H | 1 |
Takeda, J | 1 |
Kimura, K | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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Efficacy of Early Intracoronary Administration of Fasudil Hydrochloride on Myocardial Perfusion in the Primary PCI of ST-elevation Myocardial Infarction: an Prospective, Randomized and Multicenter Trial[NCT03753269] | Phase 4 | 600 participants (Anticipated) | Interventional | 2019-07-01 | Not yet recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Blood Pressure, High
Article | Year |
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[Involvement of small GTPase Rho and Rho-kinase in the pathogenesis of hypertension and hypertensive target organ damage].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Angina Pectoris; Animals; Arteriosclerosis; C | 2004 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effect of rho-kinase inhibitor in hypertensive glomerulosclerosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Collagen; Disease Models, An | 2006 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Cyclin-Dependent Kinase Inhi | 2006 |
[Role of the Rho/Rho-kinase pathway in the development of hypertensive glomerulosclerosis: renoprotective effect of Rho-kinase inhibitor in hypertensive glomerulosclerosis and its molecular mechanism].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Disease Models, Animal; Glomerulosclerosis, | 2006 |
1 trial available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Blood Pressure, High
Article | Year |
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Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Enzyme Inhibitors; Female; Forearm; Humans; Hypertens | 2001 |
37 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Blood Pressure, High
Article | Year |
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Enhanced endothelin-1/Rho-kinase signalling and coronary microvascular dysfunction in hypertensive myocardial hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arterioles; Cardiomegaly; Endothelin-1; Endo | 2017 |
Treatment with low dose fasudil for acute ischemic stroke in chronic hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cerebrovascular Circulation; Chronic Disease | 2017 |
Rho kinase activation in circulating leukocytes is related to hypertensive myocardial remodeling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Remodeling; Blood Pressure; Cardiomeg | 2018 |
Exaggerated blood pressure response to fasudil or nifedipine in hypertensive Ren-2 transgenic rats: role of altered baroreflex.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Baroreflex; Blood Pressure; Calcium Channel | 2019 |
A novel hypertensive crisis rat model established by excessive norepinephrine infusion and the potential therapeutic effects of Rho-kinase inhibitors on it.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antihypertensive Agents; Blood Pressure; Hyp | 2019 |
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; | 2014 |
Ontogenetic changes in contribution of calcium sensitization and calcium entry to blood pressure maintenance of Wistar-Kyoto and spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Blood Pressure; Calcium; Calcium C | 2015 |
Rho kinase inhibitors prevent endothelium-dependent contractions in the rat aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antihypertensive Agents; Aorta, Thor | 2009 |
Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Atmosphere Exposure Chambers | 2009 |
Role of rho-kinase in the regulation of vascular tone in hypertensive renal transplant recipients.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Case-Control Studies; Dose-Response Relationship, Dru | 2009 |
NFATc3 contributes to intermittent hypoxia-induced arterial remodeling in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Aorta, Thoracic; Bosentan; Dioxoles; | 2010 |
Optimisation of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amines; Animals; Disease Models, Animal; Hypertension | 2011 |
Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Antihypertensive Agents; Biomar | 2011 |
[Fasudil improves erectile function of hypertensive rats].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Hypertension; Male; Penile Erection; Rats; R | 2012 |
Hydroxyfasudil ameliorates bladder dysfunction in male spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Hypertension; Male; Muscle Contraction; Musc | 2012 |
Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cyclic GMP; Erectile Dysfunction; Gene Expre | 2012 |
Fasudil improves the endothelial dysfunction in the aorta of spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Endothelium, Vascular; Gene Expressio | 2012 |
[Involvement of Rho-kinase in hypertensive vascular disease--a novel therapeutic target in hypertension].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Vessels; Cardiovascular Diseases; Hype | 2002 |
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Cardiomegal | 2003 |
Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Cell Cycle Proteins; Cell Di | 2003 |
Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amides; Animals; Benzophenanthridines; Blo | 2005 |
Rho-kinase as a molecular target for insulin resistance and hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Arterioles; Cell Line; Glucos | 2006 |
ROCK controls matrix synthesis in vascular smooth muscle cells: coupling vasoconstriction to vascular remodeling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Blood Vessels; Cell Adhesion; Cell S | 2006 |
Vasodilator effects of fasudil, a Rho-kinase inhibitor, on retinal arterioles in stroke-prone spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Blood Pressure; Dose-R | 2007 |
Fasudil attenuates myocardial fibrosis in association with inhibition of monocyte/macrophage infiltration in the heart of DOCA/salt hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Cytokines; Desoxycorticoster | 2007 |
Fasudil attenuates sympathetic nervous activity in the adrenal medulla of spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Medulla; Animals; Blood Pressure; Blotting, W | 2007 |
Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Disease Models, Animal; D | 2008 |
Protein kinase C and calcium distribution in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Transporting ATPases; Cells | 1993 |
Protein kinase C modulates ischemia-induced amino acids release in the striatum of hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acids; Animals; Brain Ischemia; Corpus Striatum | 1998 |
Role of calcium/calmodulin-dependent protein kinases in expression of Fos protein in the nucleus tractus solitarii after sustained hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Baroreflex; Calcium-Calmodulin-Dependent Pro | 2000 |
Decreased insulin-sensitive Ca2+ transport in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport; Calcium; Ca | 1992 |
The contractile apparatus in vascular smooth muscle cells of spontaneously hypertensive rats possess increased calcium sensitivity: the possible role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Hypertension; Isoquinolines; Muscle | 1992 |
Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; | 1990 |
Contribution of calmodulin and protein kinase C to renin release in spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calmodulin; Hypertension; In Vitro Technique | 1990 |
Effects of a protein kinase C inhibitor (H-7) on norepinephrine release from vascular adrenergic neurons in spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Blood Vessels; Electric Stim | 1990 |
Intracellular pH in platelets from spontaneously hypertensive rats and Wistar-Kyoto rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Platelets; Hydrogen-Ion Concentration; | 1988 |
Protein kinase C-dependent and calmodulin-dependent regulation of neurotransmitter release and vascular responsiveness in spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Blood Vessels; Calmodulin; E | 1988 |