1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with B16 Melanoma in 7 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fasudil-treated tumors also displayed fewer VM channels." | 1.42 | Rho Kinase Inhibitor Fasudil Suppresses the Vasculogenic Mimicry of B16 Mouse Melanoma Cells Both In Vitro and In Vivo. ( Cai, XY; Chen, J; Fan, JQ; Li, ZY; Ren, JH; Wu, G; Xia, Y; Zhang, LL; Zhang, RG; Zhu, F, 2015) |
| "Inhibition of metastasis was time dependent, with 90% of maximum inhibition occurring by 8 h of incubation." | 1.28 | Inhibition of experimental metastasis and cell adhesion of B16F1 melanoma cells by inhibitors of protein kinase C. ( Bitonti, AJ; Dumont, JA; Jones, WD, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, Y | 1 |
| Cai, XY | 1 |
| Fan, JQ | 1 |
| Zhang, LL | 1 |
| Ren, JH | 1 |
| Chen, J | 1 |
| Li, ZY | 1 |
| Zhang, RG | 1 |
| Zhu, F | 1 |
| Wu, G | 1 |
| Ma, LJ | 1 |
| Liu, LY | 1 |
| Jiao, S | 1 |
| Wei, SM | 1 |
| Mei, YA | 1 |
| Tsubaki, M | 1 |
| Matsuoka, H | 1 |
| Yamamoto, C | 1 |
| Kato, C | 1 |
| Ogaki, M | 1 |
| Satou, T | 1 |
| Itoh, T | 1 |
| Kusunoki, T | 1 |
| Tanimori, Y | 1 |
| Nishida, S | 1 |
| Sarrabayrouse, G | 1 |
| Synaeve, C | 1 |
| Leveque, K | 1 |
| Favre, G | 1 |
| Tilkin-Mariamé, AF | 1 |
| Hakomori, S | 1 |
| Fink-Puches, R | 1 |
| Helige, C | 1 |
| Kerl, H | 1 |
| Smolle, J | 1 |
| Tritthart, HA | 1 |
| Dumont, JA | 1 |
| Jones, WD | 1 |
| Bitonti, AJ | 1 |
7 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and B16 Melanoma
| Article | Year |
|---|---|
Rho Kinase Inhibitor Fasudil Suppresses the Vasculogenic Mimicry of B16 Mouse Melanoma Cells Both In Vitro and In Vivo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Cell Line, Tumor; Cell Mo | 2015 |
Ca(2+)-inactivated K+ current is modulated by endothelin-1 in B-16 murine melanoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Line, Tumor; Cobalt; Egtazic A | 2003 |
The protein kinase C inhibitor, H7, inhibits tumor cell invasion and metastasis in mouse melanoma via suppression of ERK1/2.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Cell Line, Tumor; DNA Primers | 2007 |
Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Amino Acid Chloromethyl Keto | 2007 |
Novel endothelial cell activation factor(s) released from activated platelets which induce E-selectin expression and tumor cell adhesion to endothelial cells: a preliminary note.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Factors; Cell Adhesion | 1994 |
Inhibition of melanoma cell directional migration in vitro via different cellular targets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoimidazole Carboxamide; Animals; Calcium Channel | 1993 |
Inhibition of experimental metastasis and cell adhesion of B16F1 melanoma cells by inhibitors of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Adhesion; Isoquinolines; Lun | 1992 |