Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Asthma

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Asthma in 3 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xie, T1
Luo, G1
Zhang, Y1
Wang, X2
Wu, M1
Li, G1
LoGrasso, PV1
Feng, Y1
Doelman, CJ1
Borm, PJ1
Bast, A1

Reviews

1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Asthma

ArticleYear
Rho kinase (ROCK) inhibitors and their application to inflammatory disorders.
    Current topics in medicinal chemistry, 2009, Volume: 9, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents; Asthma; Humans; In

2009

Other Studies

2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Asthma

ArticleYear
Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2015, Volume: 45, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allergens; Animals; Asthma; Case-Control Studies; Cel

2015
Plasticisers, another burden for asthmatics?
    Agents and actions. Supplements, 1990, Volume: 31

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Asthma; Diethylhexyl Phthalate; Dose-Respons

1990