1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Anoxia, Brain in 5 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Signal transduction systems that modulate protein kinase C (PKC) also can modulate the toxic effects of anoxia and NO." | 1.29 | Neuroprotection by peptide growth factors against anoxia and nitric oxide toxicity requires modulation of protein kinase C. ( Boccone, L; Maiese, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, J | 1 |
| Li, QY | 1 |
| Wang, X | 1 |
| Sun, CH | 1 |
| Lu, CZ | 1 |
| Xiao, BG | 1 |
| Shin, HK | 1 |
| Salomone, S | 1 |
| Potts, EM | 1 |
| Lee, SW | 1 |
| Millican, E | 1 |
| Noma, K | 1 |
| Huang, PL | 1 |
| Boas, DA | 1 |
| Liao, JK | 1 |
| Moskowitz, MA | 1 |
| Ayata, C | 1 |
| Maiese, K | 2 |
| Boccone, L | 1 |
| Yao, H | 1 |
| Gu, XQ | 1 |
| Douglas, RM | 1 |
| Haddad, GG | 1 |
5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Anoxia, Brain
| Article | Year |
|---|---|
Fasudil protects hippocampal neurons against hypoxia-reoxygenation injury by suppressing microglial inflammatory responses in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Anti-Inflammatory Agents, | 2010 |
Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Brain Ischemia; Cerebrovascul | 2007 |
Neuroprotection by peptide growth factors against anoxia and nitric oxide toxicity requires modulation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Down-Regulation; Epidermal Growth Factor; Fi | 1995 |
Protein kinase C modulates the protective ability of peptide growth factors during anoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Death; Cells, Cultured; Enzyme Activati | 1994 |
Role of Na(+)/H(+) exchanger during O(2) deprivation in mouse CA1 neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acids; Alkaloids; Animals; Benzophenanthridines; Cell | 2001 |