1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Angina at Rest in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fasudil was effective in preventing ACh-induced coronary artery spasm and resultant myocardial ischemia in patients with vasospastic angina." | 2.70 | Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina. ( Masumoto, A; Mohri, M; Shimokawa, H; Takeshita, A; Urakami, L; Usui, M, 2002) |
| "An 86-year-old woman was admitted with unstable angina pectoris." | 1.32 | [Inhibition of Rho-kinase by fasudil preventing anginal attacks associated with spastic angina: a case report]. ( Fukumoto, Y; Hiroki, J; Hirooka, Y; Shimokawa, H; Takeshita, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hiroki, J | 1 |
| Fukumoto, Y | 1 |
| Shimokawa, H | 2 |
| Hirooka, Y | 1 |
| Takeshita, A | 2 |
| Masumoto, A | 1 |
| Mohri, M | 1 |
| Urakami, L | 1 |
| Usui, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Telmisartan (Micardis) For the Prevention of Acute Graft vs. Host Disease Post Allogeneic Hematopoietic Stem Cell Transplantation[NCT02338232] | 32 participants (Actual) | Interventional | 2015-07-07 | Terminated (stopped due to Lack of Accrual) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Angina at Rest
| Article | Year |
|---|---|
Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Aged; Angina, Unstable; Coronary Angio | 2002 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Angina at Rest
| Article | Year |
|---|---|
[Inhibition of Rho-kinase by fasudil preventing anginal attacks associated with spastic angina: a case report].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Aged, 80 and over; Angina, Unstable; Angioplast | 2004 |