1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Allergic Neuritis, Experimental in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fasudil treatment was associated with a significant reduction in secretion of IFN-γ; by contrast, secretion of IL-4 was almost the same in the fasudil- and PBS-treated groups." | 1.37 | Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis. ( Kawamura, N; Kira, J; Matsushita, T; Minohara, M; Piao, H; Pineda, AA; Shimokawa, H; Sun, X; Yamasaki, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 1 |
| Liu, B | 1 |
| Wang, Y | 1 |
| Xiao, B | 1 |
| Pineda, AA | 1 |
| Minohara, M | 1 |
| Kawamura, N | 1 |
| Matsushita, T | 1 |
| Yamasaki, R | 1 |
| Sun, X | 1 |
| Piao, H | 1 |
| Shimokawa, H | 1 |
| Kira, J | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Allergic Neuritis, Experimental
| Article | Year |
|---|---|
Effect of fasudil on experimental autoimmune neuritis and its mechanisms of action.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Female; Interferon-gamma; Interleukins; Mice | 2020 |
Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antigen-Presenting Cells; Carrier Proteins; | 2011 |