1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Adjuvant Arthritis in 4 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JH | 1 |
| Lee, GE | 1 |
| Lee, SD | 1 |
| Hien, TT | 1 |
| Kim, S | 1 |
| Yang, JW | 1 |
| Cho, JH | 1 |
| Ko, H | 1 |
| Lim, SC | 1 |
| Kim, YG | 1 |
| Kang, KW | 1 |
| Kim, YC | 1 |
| He, Y | 1 |
| Xu, H | 1 |
| Liang, L | 1 |
| Zhan, Z | 1 |
| Yang, X | 1 |
| Yu, X | 1 |
| Ye, Y | 1 |
| Sun, L | 1 |
| Okamoto, H | 1 |
| Yoshio, T | 1 |
| Kaneko, H | 1 |
| Yamanaka, H | 1 |
| Yoshimi, E | 1 |
| Kumakura, F | 1 |
| Hatori, C | 1 |
| Hamachi, E | 1 |
| Iwashita, A | 1 |
| Ishii, N | 1 |
| Terasawa, T | 1 |
| Shimizu, Y | 1 |
| Takeshita, N | 1 |
4 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Adjuvant Arthritis
| Article | Year |
|---|---|
Discovery of novel 2,5-dioxoimidazolidine-based P2X(7) receptor antagonists as constrained analogues of KN62.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arthritis, Experimental; Carrageenan; Cattle | 2015 |
Antiinflammatory effect of Rho kinase blockade via inhibition of NF-kappaB activation in rheumatoid arthritis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Amides; Animals; Arthritis, Experimental; Arthr | 2008 |
Inhibition of NF-kappaB signaling by fasudil as a potential therapeutic strategy for rheumatoid arthritis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arthritis, Experimental; Arthritis, Rheumato | 2010 |
Antinociceptive effects of AS1892802, a novel Rho kinase inhibitor, in rat models of inflammatory and noninflammatory arthritis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflamm | 2010 |