1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Acute Disease in 5 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicenter, double-blind, placebo-controlled study was conducted to assess the efficacy and safety of fasudil, a Rho-kinase inhibitor (RKI), in the treatment of acute ischemic stroke." | 9.11 | Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial. ( Hirai, S; Ohtomo, E; Satoh, S; Seto, M; Shibuya, M, 2005) |
| "A multicenter, double-blind, placebo-controlled study was conducted to assess the efficacy and safety of fasudil, a Rho-kinase inhibitor (RKI), in the treatment of acute ischemic stroke." | 5.11 | Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial. ( Hirai, S; Ohtomo, E; Satoh, S; Seto, M; Shibuya, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Detter, MR | 1 |
| Shenkar, R | 1 |
| Benavides, CR | 1 |
| Neilson, CA | 1 |
| Moore, T | 1 |
| Lightle, R | 1 |
| Hobson, N | 1 |
| Shen, L | 1 |
| Cao, Y | 1 |
| Girard, R | 1 |
| Zhang, D | 1 |
| Griffin, E | 1 |
| Gallione, CJ | 1 |
| Awad, IA | 1 |
| Marchuk, DA | 1 |
| Shibuya, M | 1 |
| Hirai, S | 1 |
| Seto, M | 1 |
| Satoh, S | 1 |
| Ohtomo, E | 1 |
| Nishizawa, S | 1 |
| Zhang, JH | 1 |
| Chida, M | 1 |
| Voelkel, NF | 1 |
| Hashida, M | 1 |
| Fukushima, A | 1 |
| Zhang, J | 1 |
| Kodama, H | 1 |
| Ueno, H | 1 |
1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Acute Disease
| Article | Year |
|---|---|
[Basic research and treatment for cerebral vasospasm after subarachnoid hemorrhage: the present and future prospects].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Angioplasty, Balloon; Calcium Channel | 2008 |
1 trial available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Acute Disease
| Article | Year |
|---|---|
Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Aged; Brain Ischemia; Dose-Response Re | 2005 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Acute Disease
| Article | Year |
|---|---|
Novel Murine Models of Cerebral Cavernous Malformations.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Animals; Apoptosis Regulatory Proteins | 2020 |
Effects of acute and chronic hypoxia on rat lung cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Animals; Blotting, Northern; Chronic D | 1996 |
Involvement of superoxide generated by polymorphonuclear leukocytes in endotoxin-induced uveitis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Animals; Blotting, Western; Dose-Respo | 2000 |