Compounds > 1-(5--phospho-beta-d-ribofuranosyl)barbituric-acid

1-(5--phospho-beta-d-ribofuranosyl)barbituric-acid and Brain-Injuries

1-(5--phospho-beta-d-ribofuranosyl)barbituric-acid has been researched along with Brain-Injuries* in 1 studies

Other Studies

1 other study(ies) available for 1-(5--phospho-beta-d-ribofuranosyl)barbituric-acid and Brain-Injuries

Article	Year
Expression of serine/threonine kinase receptors in traumatic brain injury. Neuroreport, 1997, Jan-20, Volume: 8, Issue:2 The aim of this study was to investigate the expression of serine/threonine kinase receptors in the brain following traumatic brain injury. We report here that, the recently cloned and characterized bone morphogenetic protein (BMP) receptor type II (BMPR-II) and the activin receptor type IA (ActR-1) Act: mRNAs were simultaneously up-regulated in neurones in the dentate gyrus 6 h after a mild cerebral contusion injury. This findings was specific for these receptors since other investigated genes (i.e. ActR-II, ActR-IB, trkB and c-fos) showed other temporal patterns. These data suggest that type I and type II receptors act together in signal transduction in vivo and that BMPs may be involved in neuronal plasticity after traumatic brain injury. Topics: Animals; Bone Morphogenetic Protein Receptors, Type II; Brain Injuries; In Situ Hybridization; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Uridine Monophosphate	1997

Article

Year

Expression of serine/threonine kinase receptors in traumatic brain injury.

Neuroreport, 1997, Jan-20, Volume: 8, Issue:2

The aim of this study was to investigate the expression of serine/threonine kinase receptors in the brain following traumatic brain injury. We report here that, the recently cloned and characterized bone morphogenetic protein (BMP) receptor type II (BMPR-II) and the activin receptor type IA (ActR-1) Act: mRNAs were simultaneously up-regulated in neurones in the dentate gyrus 6 h after a mild cerebral contusion injury. This findings was specific for these receptors since other investigated genes (i.e. ActR-II, ActR-IB, trkB and c-fos) showed other temporal patterns. These data suggest that type I and type II receptors act together in signal transduction in vivo and that BMPs may be involved in neuronal plasticity after traumatic brain injury.

Topics: Animals; Bone Morphogenetic Protein Receptors, Type II; Brain Injuries; In Situ Hybridization; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Uridine Monophosphate

1997