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1-(4-carboxyphenyl)-3,3-dimethyltriazene and Malignant Melanoma

1-(4-carboxyphenyl)-3,3-dimethyltriazene has been researched along with Malignant Melanoma in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benvenuto, J; Farquhar, D1
Giraldi, T; Lassiani, L; Nisi, C; Sava, G1
Bleehen, NM; Brampton, M; Calvert, AH; Harper, P; Judson, I; Kaye, SB; Lee, SM1
Calvert, AH; Carmichael, J; Foster, BJ; Goodard, PM; Gumbrell, LA; Harris, AL; Jones, M; Newell, DR1
Crowther, D; Lee, SM; Margison, GP; Thatcher, N1

Trials

3 trial(s) available for 1-(4-carboxyphenyl)-3,3-dimethyltriazene and Malignant Melanoma

ArticleYear
A Cancer Research Campaign (CRC) phase II trial of CB10-277 given by 24 hour infusion for malignant melanoma.
    British journal of cancer, 1994, Volume: 70, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Triazenes

1994
Preclinical, phase I and pharmacokinetic studies with the dimethyl phenyltriazene CB10-277.
    British journal of cancer, 1993, Volume: 67, Issue:2

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Dacarbazine; Disease Models, Animal; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasms; Species Specificity; Transplantation, Heterologous; Triazenes

1993
In vivo depletion of O6-alkylguanine-DNA-alkyltransferase in lymphocytes and melanoma of patients treated with CB 10-277, a new DTIC analogue.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphocytes; Male; Melanoma; Methyltransferases; Middle Aged; O(6)-Methylguanine-DNA Methyltransferase; Skin Neoplasms; Triazenes

1992

Other Studies

2 other study(ies) available for 1-(4-carboxyphenyl)-3,3-dimethyltriazene and Malignant Melanoma

ArticleYear
1-Aryl-3,3-dimethyltriazenes: potential central nervous system active analogues of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC).
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug Evaluation, Preclinical; Ependymoma; Leukemia L1210; Melanoma; Mice; Mice, Inbred Strains; Structure-Activity Relationship

1984
Antimetastatic action and hematological toxicity of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide used as prophylactic adjuvants to surgical tumor removal in mice bearing B16 melanoma.
    Cancer research, 1984, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Dacarbazine; Melanoma; Mice; Mice, Inbred Strains; Triazenes

1984