Page last updated: 2024-10-31

1-(3-trifluoromethylphenyl)piperazine and Chemical Dependence

1-(3-trifluoromethylphenyl)piperazine has been researched along with Chemical Dependence in 12 studies

1-(3-trifluoromethylphenyl)piperazine: acts as serotonin agonist; structure
1-(3-(trifluoromethyl)phenyl)piperazine : A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.

Research Excerpts

ExcerptRelevanceReference
"Seizures are induced in some patients even at low doses."2.47The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine. ( Beasley, DM; Gee, P; Schep, LJ; Slaughter, RJ; Vale, JA, 2011)
"Drug abuse affects a significant number of individuals of all ages."2.42Common drugs of abuse--Part II. ( Cuddy, ML, 2004)
"A total of 972 drug abusers and high-risk individuals were recruited from acute, rehabilitation, and high-risk settings between 1 November 2011 and 31 July 2013."1.42Surveillance of emerging drugs of abuse in Hong Kong: validation of an analytical tool. ( Ching, CK; Chong, YK; Lee, C; Mak, TW; Ng, C; Tang, M; Tse, ML; Wong, W, 2015)
" The use of these party pills has been associated with adverse health effects."1.35Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand. ( Girling, M; Sweetsur, P; Wilkins, C, 2008)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (58.33)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tang, M1
Ching, CK1
Tse, ML1
Ng, C1
Lee, C1
Chong, YK1
Wong, W1
Mak, TW2
Lecompte, Y1
Roussel, O1
Perrin, M1
Wood, DM1
Button, J1
Lidder, S1
Ramsey, J1
Holt, DW1
Dargan, PI1
Wilkins, C1
Sweetsur, P1
Girling, M1
Antia, U2
Tingle, MD2
Russell, BR2
Poon, WT1
Lai, CF1
Lui, MC1
Chan, AY1
Logan, BK1
Costantino, AG1
Rieders, EF1
Sanders, D1
Łukasik-Głebock, M1
Sommerfeld, K1
Nawrocka, K1
Schep, LJ1
Slaughter, RJ1
Vale, JA1
Beasley, DM1
Gee, P1
Cuddy, ML1
Elliott, S1
Smith, C1

Reviews

4 reviews available for 1-(3-trifluoromethylphenyl)piperazine and Chemical Dependence

ArticleYear
[1-benzylpiperazine (BZP) and 1-(3-trifluorométhylphényl)pipérazine (TFMPP): emergence of two agents which lead to misuse].
    Annales pharmaceutiques francaises, 2008, Volume: 66, Issue:2

    Topics: France; Humans; Illicit Drugs; Piperazines; Serotonin Receptor Agonists; Substance-Related Disorders

2008
'Party pill' drugs--BZP and TFMPP.
    The New Zealand medical journal, 2009, Dec-11, Volume: 122, Issue:1307

    Topics: Dosage Forms; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Illicit Drugs; Ma

2009
The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:3

    Topics: Designer Drugs; Fever; Humans; Illicit Drugs; Piperazines; Seizures; Serotonin Receptor Agonists; Su

2011
Common drugs of abuse--Part II.
    The Journal of practical nursing, 2004,Spring, Volume: 54, Issue:1

    Topics: 4-Butyrolactone; Catha; Designer Drugs; Dibenzothiazepines; Diterpenes; Diterpenes, Clerodane; DOM 2

2004

Other Studies

8 other studies available for 1-(3-trifluoromethylphenyl)piperazine and Chemical Dependence

ArticleYear
Surveillance of emerging drugs of abuse in Hong Kong: validation of an analytical tool.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2015, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Cross-Sectional Studies; Female; Hair; Health Surveys;

2015
Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP).
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:4

    Topics: Adolescent; Bruxism; Dissociative Disorders; Electrocardiography; Gas Chromatography-Mass Spectromet

2008
Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand.
    Drug and alcohol review, 2008, Volume: 27, Issue:6

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Central Nervous System Stimulants; Drug Combinations; Female

2008
In vivo interactions between BZP and TFMPP (party pill drugs).
    The New Zealand medical journal, 2009, Sep-25, Volume: 122, Issue:1303

    Topics: Administration, Oral; Adult; Drug Interactions; Follow-Up Studies; Humans; Illicit Drugs; Male; New

2009
Piperazines: a new class of drug of abuse has landed in Hong Kong.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2010, Volume: 16, Issue:1

    Topics: Adult; Humans; Male; Piperazines; Substance-Related Disorders

2010
Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:9

    Topics: Antidepressive Agents; Cross Reactions; False Positive Reactions; Hallucinogens; Humans; Illicit Dru

2010
Legal highs toxicity--symptomatology and clinical diagnosis in case series.
    Przeglad lekarski, 2010, Volume: 67, Issue:8

    Topics: Adult; Female; Humans; Male; Piperazines; Psychotropic Drugs; Substance Abuse Detection; Substance-R

2010
Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP.
    Journal of analytical toxicology, 2008, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Cause of Death; Chromatography, High Pressure Liquid; Humans; Male; Piperazines;

2008