1-(3-chlorophenyl)piperazine has been researched along with Urinary Incontinence, Stress in 3 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Urinary Incontinence, Stress: Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the role of spinal serotonergic mechanisms in preventing stress urinary incontinence (SUI) during sneezing, we investigated the effect of intrathecal (it) application of 8-OH-DPAT (a 5-HT(1A) agonist), mCPP (a 5-HT(2B/2C) agonist), and fluoxetine (a serotonin reuptake inhibitor) using a rat model that can examine the neurally evoked continence reflex during sneezing." | 3.75 | Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats. ( Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Kitta, T; Miyazato, M; Sugaya, K; Yoshimura, N, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allerton, CM | 1 |
| Andrews, MD | 1 |
| Blagg, J | 1 |
| Ellis, D | 1 |
| Evrard, E | 1 |
| Green, MP | 1 |
| Liu, KK | 1 |
| McMurray, G | 1 |
| Ralph, M | 1 |
| Sanderson, V | 1 |
| Ward, R | 1 |
| Watson, L | 1 |
| Kawamorita, N | 1 |
| Kaiho, Y | 2 |
| Miyazato, M | 2 |
| Arai, Y | 2 |
| Yoshimura, N | 2 |
| Kamo, I | 1 |
| Kitta, T | 1 |
| Chancellor, MB | 1 |
| Sugaya, K | 1 |
| de Groat, WC | 1 |
3 other studies available for 1-(3-chlorophenyl)piperazine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Design and synthesis of pyridazinone-based 5-HT(2C) agonists.
Topics: Animals; Dogs; Drug Design; Humans; Piperazines; Pyridazines; Receptor, Serotonin, 5-HT2A; Receptor, | 2009 |
Roles of the spinal glutamatergic pathway activated through α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and its interactions with spinal noradrenergic and serotonergic pathways in the rat urethral continence mechanisms.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Norepinephrine; Piperazines; Quinoxa | 2015 |
Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Fluoxetine; Piperazines; Pressure; Pyridine | 2009 |