1-(3-chlorophenyl)piperazine has been researched along with Tourette Syndrome in 1 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cath, DC | 1 |
| Gijsman, HJ | 1 |
| Schoemaker, RC | 1 |
| van Griensven, JM | 1 |
| Troost, N | 1 |
| van Kempen, GM | 1 |
| Cohen, AF | 1 |
1 trial available for 1-(3-chlorophenyl)piperazine and Tourette Syndrome
| Article | Year |
|---|---|
The effect of m-CPP on tics and obsessive-compulsive phenomena in Gilles de la Tourette syndrome.
Topics: Adult; Aged; Compulsive Behavior; Cross-Over Studies; Double-Blind Method; Female; Humans; Impulsive | 1999 |