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1-(3-chlorophenyl)piperazine and Serotonin Syndrome

1-(3-chlorophenyl)piperazine has been researched along with Serotonin Syndrome in 1 studies

1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baumgarten, HG1
Grozdanovic, Z1

Reviews

1 review available for 1-(3-chlorophenyl)piperazine and Serotonin Syndrome

ArticleYear
Role of serotonin in obsessive-compulsive disorder.
    The British journal of psychiatry. Supplement, 1998, Issue:35

    Topics: Biogenic Monoamines; Fenfluramine; Humans; Neuropeptides; Obsessive-Compulsive Disorder; Piperazines

1998