1-(3-chlorophenyl)piperazine has been researched along with Psychotic Disorders in 2 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results demonstrate that clozapine treatment has potent serotonin antagonist effects in patients with schizophrenia." | 9.07 | Effects of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia. ( Benkelfat, C; Gutierrez-Esteinou, R; Hadd, K; Hsiao, J; Lawlor, BA; Murphy, DL; Owen, RR; Pickar, D, 1993) |
| "These results demonstrate that clozapine treatment has potent serotonin antagonist effects in patients with schizophrenia." | 5.07 | Effects of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia. ( Benkelfat, C; Gutierrez-Esteinou, R; Hadd, K; Hsiao, J; Lawlor, BA; Murphy, DL; Owen, RR; Pickar, D, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Owen, RR | 1 |
| Gutierrez-Esteinou, R | 1 |
| Hsiao, J | 1 |
| Hadd, K | 1 |
| Benkelfat, C | 1 |
| Lawlor, BA | 1 |
| Murphy, DL | 1 |
| Pickar, D | 1 |
| Serretti, A | 1 |
| Lilli, R | 1 |
| Lorenzi, C | 1 |
| Lattuada, E | 1 |
| Cusin, C | 1 |
| Smeraldi, E | 1 |
1 trial available for 1-(3-chlorophenyl)piperazine and Psychotic Disorders
| Article | Year |
|---|---|
Effects of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia.
Topics: Adult; Body Temperature; Clozapine; Female; Fluphenazine; Hospitalization; Humans; Hydrocortisone; I | 1993 |
1 other study available for 1-(3-chlorophenyl)piperazine and Psychotic Disorders
| Article | Year |
|---|---|
Tryptophan hydroxylase gene and major psychoses.
Topics: Adult; Bipolar Disorder; DNA Mutational Analysis; DNA Primers; Female; Gene Expression; Gene Frequen | 2001 |