1-(3-chlorophenyl)piperazine has been researched along with Priapism in 2 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Priapism: A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with the antidepressant trazodone has been associated with the occurrence of prolonged penile erection and priapism." | 5.07 | Pathophysiology of prolonged penile erection associated with trazodone use. ( Azadzoi, KM; Blanco, R; Goldstein, I; Krane, RJ; Nadig, PW; Pittard, JT; Saenz de Tejada, I; Ware, JC, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thavundayil, JX | 1 |
| Hambalek, R | 1 |
| Kin, NM | 1 |
| Krishnan, B | 1 |
| Lal, S | 1 |
| Saenz de Tejada, I | 1 |
| Ware, JC | 1 |
| Blanco, R | 1 |
| Pittard, JT | 1 |
| Nadig, PW | 1 |
| Azadzoi, KM | 1 |
| Krane, RJ | 1 |
| Goldstein, I | 1 |
1 trial available for 1-(3-chlorophenyl)piperazine and Priapism
| Article | Year |
|---|---|
Pathophysiology of prolonged penile erection associated with trazodone use.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Humans; In Vitro Technique | 1991 |
1 other study available for 1-(3-chlorophenyl)piperazine and Priapism
| Article | Year |
|---|---|
Prolonged penile erections induced by hydroxyzine: possible mechanism of action.
Topics: Adult; Humans; Hydroxyzine; Insect Bites and Stings; Male; Models, Molecular; Molecular Conformation | 1994 |