1-(3-chlorophenyl)piperazine has been researched along with Phobic Disorders in 6 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Phobic Disorders: Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Challenge studies have demonstrated that subjects with social anxiety disorder have a sensitivity to carbon dioxide, cholecystokinin, and caffeine somewhere between that of panic disorder patients and normal controls." | 4.80 | Brain mechanisms of social anxiety disorder. ( Bell, CJ; Malizia, AL; Nutt, DJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leveleki, C | 1 |
| Sziray, N | 1 |
| Levay, G | 1 |
| Barsvári, B | 1 |
| Soproni, K | 1 |
| Mikics, E | 1 |
| Haller, J | 1 |
| Guitton, MJ | 1 |
| Klin, Y | 1 |
| Dudai, Y | 1 |
| Simeon, D | 2 |
| Hollander, E | 2 |
| Stein, DJ | 2 |
| DeCaria, C | 2 |
| Cohen, LJ | 1 |
| Saoud, JB | 1 |
| Islam, N | 1 |
| Hwang, M | 1 |
| Kwon, J | 1 |
| Weiller, F | 1 |
| Cohen, L | 1 |
| Liebowitz, M | 1 |
| Nutt, DJ | 1 |
| Bell, CJ | 1 |
| Malizia, AL | 1 |
| Griebel, G | 1 |
| Misslin, R | 1 |
| Pawlowski, M | 1 |
| Vogel, E | 1 |
1 review available for 1-(3-chlorophenyl)piperazine and Phobic Disorders
| Article | Year |
|---|---|
Brain mechanisms of social anxiety disorder.
Topics: Animals; Brain; Caffeine; Carbon Dioxide; Cholecystokinin; Dopamine; Fear; Fenfluramine; Humans; Pan | 1998 |
2 trials available for 1-(3-chlorophenyl)piperazine and Phobic Disorders
| Article | Year |
|---|---|
Induction of depersonalization by the serotonin agonist meta-chlorophenylpiperazine.
Topics: Adult; Animals; Arousal; Borderline Personality Disorder; Brain; Depersonalization; Double-Blind Met | 1995 |
Serotonergic function in social phobia: comparison to normal control and obsessive-compulsive disorder subjects.
Topics: Adult; Analysis of Variance; Anxiety; Case-Control Studies; Female; Humans; Hydrocortisone; Male; Ne | 1998 |
3 other studies available for 1-(3-chlorophenyl)piperazine and Phobic Disorders
| Article | Year |
|---|---|
Pharmacological evaluation of the stress-induced social avoidance model of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Buspirone; Chlordiazepoxide; Diazepam; Disea | 2006 |
Taste-dependent sociophobia: when food and company do not mix.
Topics: Animals; Antimanic Agents; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Food; Inte | 2008 |
m-Chlorophenylpiperazine enhances neophobic and anxious behaviour in mice.
Topics: Analysis of Variance; Animals; Anxiety; Choice Behavior; Exploratory Behavior; Male; Mice; Mice, Inb | 1991 |