1-(3-chlorophenyl)piperazine has been researched along with Necrosis in 1 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral dosing of 58 reduced food intake in an acute rat feeding model, which could be completely reversed by a selective 5-HT2C antagonist and caused a reduction in body weight gain in a 4-day rat model." | 1.34 | Discovery of (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol- 6(2H)-one, a selective, orally active agonist of the 5-HT(2C) receptor. ( Cao, X; Cullen, MJ; Devenny, J; Hung, CP; Janovitz, E; Keim, WJ; Lehman-McKeeman, L; Malley, MF; Malmstrom, SE; Miller, KJ; Narayanan, R; Pelleymounter, MA; Qu, Q; Robl, JA; Rohrbach, KW; Rossi, K; Thomas, MA; Ung, T; Varnes, JG; Wacker, DA; Wu, G; Zhang, G; Zuvich, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wacker, DA | 1 |
| Varnes, JG | 1 |
| Malmstrom, SE | 1 |
| Cao, X | 1 |
| Hung, CP | 1 |
| Ung, T | 1 |
| Wu, G | 1 |
| Zhang, G | 1 |
| Zuvich, E | 1 |
| Thomas, MA | 1 |
| Keim, WJ | 1 |
| Cullen, MJ | 1 |
| Rohrbach, KW | 1 |
| Qu, Q | 1 |
| Narayanan, R | 1 |
| Rossi, K | 1 |
| Janovitz, E | 1 |
| Lehman-McKeeman, L | 1 |
| Malley, MF | 1 |
| Devenny, J | 1 |
| Pelleymounter, MA | 1 |
| Miller, KJ | 1 |
| Robl, JA | 1 |
1 other study available for 1-(3-chlorophenyl)piperazine and Necrosis
| Article | Year |
|---|---|
Discovery of (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol- 6(2H)-one, a selective, orally active agonist of the 5-HT(2C) receptor.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Blood-Brain Barrier; Cell Line; Conditioning, Op | 2007 |