1-(3-chlorophenyl)piperazine has been researched along with Liver Dysfunction in 1 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In healthy volunteers, nefazodone was rapidly absorbed after which the plasma concentrations declined with an apparent elimination half-life ranging from 2." | 2.67 | Influence of hepatic impairment on the pharmacokinetics of nefazodone and two of its metabolites after single and multiple oral doses. ( Bernard, N; Cuisinaud, G; Ferry, N; Rougier, P; Sassard, J; Trepo, C, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferry, N | 1 |
| Bernard, N | 1 |
| Cuisinaud, G | 1 |
| Rougier, P | 1 |
| Trepo, C | 1 |
| Sassard, J | 1 |
1 trial available for 1-(3-chlorophenyl)piperazine and Liver Dysfunction
| Article | Year |
|---|---|
Influence of hepatic impairment on the pharmacokinetics of nefazodone and two of its metabolites after single and multiple oral doses.
Topics: Adolescent; Adult; Antidepressive Agents; Female; Humans; Liver Diseases; Male; Middle Aged; Piperaz | 1994 |