1-(3-chlorophenyl)piperazine has been researched along with Kidney Diseases in 2 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Serial blood samples for pharmacokinetic analysis were collected for 48 h following each dose and plasma samples were assayed for NEF, HO-NEF and mCPP by a validated HPLC method." | 1.29 | Single-dose pharmacokinetics of nefazodone in healthy young and elderly subjects and in subjects with renal or hepatic impairment. ( Barbhaiya, RH; Greene, DS; Shukla, UA, 1995) |
| " Single trough blood samples just prior to each morning dose (Cmin) and serial samples after the dose on day 8 were obtained at each dose level for pharmacokinetic analysis." | 1.29 | Steady-state pharmacokinetics of nefazodone in subjects with normal and impaired renal function. ( Barbhaiya, RH; Brady, ME; Greene, DS; Shukla, UA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbhaiya, RH | 2 |
| Shukla, UA | 2 |
| Greene, DS | 2 |
| Brady, ME | 1 |
2 other studies available for 1-(3-chlorophenyl)piperazine and Kidney Diseases
| Article | Year |
|---|---|
Single-dose pharmacokinetics of nefazodone in healthy young and elderly subjects and in subjects with renal or hepatic impairment.
Topics: Administration, Oral; Adult; Age Factors; Aged; Antidepressive Agents; Female; Humans; Kidney Diseas | 1995 |
Steady-state pharmacokinetics of nefazodone in subjects with normal and impaired renal function.
Topics: Antidepressive Agents; Female; Humans; Kidney Diseases; Male; Middle Aged; Piperazines; Serotonin Re | 1995 |