1-(3-chlorophenyl)piperazine has been researched along with Glucose Intolerance in 2 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The burden of type 2 diabetes and its associated premature morbidity and mortality is rapidly growing, and the need for novel efficacious treatments is pressing." | 1.34 | Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. ( Butler, AA; Clifton, PG; Elmquist, JK; Evans, ML; Heisler, LK; Lam, DD; McCrimmon, RJ; Oksanen, LJ; Rochford, JJ; Semple, RK; Sutton, GM; Thornton-Jones, ZD; Yueh, CY; Zhou, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nonogaki, K | 1 |
| Kaji, T | 1 |
| Zhou, L | 1 |
| Sutton, GM | 1 |
| Rochford, JJ | 1 |
| Semple, RK | 1 |
| Lam, DD | 1 |
| Oksanen, LJ | 1 |
| Thornton-Jones, ZD | 1 |
| Clifton, PG | 1 |
| Yueh, CY | 1 |
| Evans, ML | 1 |
| McCrimmon, RJ | 1 |
| Elmquist, JK | 1 |
| Butler, AA | 1 |
| Heisler, LK | 1 |
2 other studies available for 1-(3-chlorophenyl)piperazine and Glucose Intolerance
| Article | Year |
|---|---|
Pharmacological stimulation of serotonin 5-HT1B receptors enhances increases in plasma active glucagon-like peptide-1 levels induced by dipeptidyl peptidase-4 inhibition independently of feeding in mice.
Topics: Administration, Oral; Animals; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Resp | 2015 |
Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways.
Topics: Absorptiometry, Photon; Animals; Blotting, Western; Diabetes Mellitus, Type 2; Gene Expression; Gluc | 2007 |