1-(3-chlorophenyl)piperazine has been researched along with Epilepsy, Absence in 2 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jakus, R | 1 |
| Graf, M | 1 |
| Juhasz, G | 1 |
| Gerber, K | 1 |
| Levay, G | 1 |
| Halasz, P | 1 |
| Bagdy, G | 1 |
| Bercovici, E | 1 |
| Cortez, MA | 1 |
| Snead, OC | 1 |
2 other studies available for 1-(3-chlorophenyl)piperazine and Epilepsy, Absence
| Article | Year |
|---|---|
5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy.
Topics: Action Potentials; Aminopyridines; Animals; Citalopram; Disease Models, Animal; Dose-Response Relati | 2003 |
5-HT2 modulation of AY-9944 induced atypical absence seizures.
Topics: Amphetamines; Animals; Anticholesteremic Agents; Epilepsy, Absence; Ketanserin; Piperazines; Rats; R | 2007 |