1-(3-chlorophenyl)piperazine has been researched along with Dyskinesia, Drug-Induced in 6 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Present study was designed to monitor the responsiveness of 5HT (5-Hydroxytryptamine) -2C receptors following the long-term administration of haloperidol in rats." | 1.34 | Neurochemical and behavioral effects of m-CPP in a rat model of tardive dyskinesia. ( Haleem, DJ; Ikram, H; Samad, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samad, N | 2 |
| Haleem, MA | 1 |
| Haleem, DJ | 2 |
| Simansky, KJ | 1 |
| Dave, KD | 1 |
| Inemer, BR | 1 |
| Nicklous, DM | 1 |
| Padron, JM | 1 |
| Aloyo, VJ | 1 |
| Romano, AG | 1 |
| Ikram, H | 1 |
| De Deurwaèrdere, P | 1 |
| Chesselet, MF | 2 |
| Mehta, A | 1 |
| Eberle-Wang, K | 1 |
| Gong, L | 1 |
| Kostrzewa, RM | 1 |
6 other studies available for 1-(3-chlorophenyl)piperazine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Behavioral effects of 1-(m-chlorophenyl)piperazine (m-CPP) in a rat model of tardive dyskinesia.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dopamine Antagonists; Dyskinesia, Drug-I | 2008 |
A 5-HT2C agonist elicits hyperactivity and oral dyskinesia with hypophagia in rabbits.
Topics: Acrylamides; Animals; Area Under Curve; Dose-Response Relationship, Drug; Drug Interactions; Dyskine | 2004 |
Neurochemical and behavioral effects of m-CPP in a rat model of tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striat | 2007 |
Nigrostriatal lesions alter oral dyskinesia and c-Fos expression induced by the serotonin agonist 1-(m-chlorophenyl)piperazine in adult rats.
Topics: Animals; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Gene Expression Regulation; Genes, fos | 2000 |
Increased m-CPP-induced oral dyskinesia after lesion of serotonergic neurons.
Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Dyskinesia, Drug-Induced; Male; Piperazines; Rat | 2001 |
Supersensitized oral responses to a serotonin agonist in neonatal 6-OHDA-treated rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Drug Resistance; Dyskinesia, Drug-Induced; Female; Oxid | 1992 |