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1-(3-chlorophenyl)piperazine and Drug Withdrawal Symptoms

1-(3-chlorophenyl)piperazine has been researched along with Drug Withdrawal Symptoms in 8 studies

1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bull, EJ1
Hutson, PH1
Fone, KC1
Romandini, S1
Cervo, L2
Samanin, R2
Rochat, C1
Poggesi, E1
Mennini, T1
Buydens-Branchey, L1
Branchey, M1
Fergeson, P1
Hudson, J1
McKernin, C1
Kalkman, HO1
Jung, ME1
Wallis, CJ1
Gatch, MB1
Lal, H1
Valeri, P1
Pimpinella, G1
Troiani, MP1
Morrone, LA1
Romanelli, L1
van der Laan, JW1
Hillen, FC1

Reviews

1 review available for 1-(3-chlorophenyl)piperazine and Drug Withdrawal Symptoms

ArticleYear
Hypersensitivity to meta-chlorophenylpiperazine (mCPP) in migraine and drug withdrawal.
    International journal of clinical pharmacology research, 1997, Volume: 17, Issue:2-3

    Topics: Animals; Depression; Humans; Migraine Disorders; Piperazines; Rats; Serotonin Receptor Agonists; Spe

1997

Trials

1 trial available for 1-(3-chlorophenyl)piperazine and Drug Withdrawal Symptoms

ArticleYear
Hormonal, psychological, and alcohol craving changes after m-chlorophenylpiperazine administration in alcoholics.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:2

    Topics: Adult; Alcoholism; Double-Blind Method; Ethanol; Euphoria; Humans; Hydrocortisone; Male; Middle Aged

1997

Other Studies

6 other studies available for 1-(3-chlorophenyl)piperazine and Drug Withdrawal Symptoms

ArticleYear
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.
    Neuropharmacology, 2003, Volume: 44, Issue:4

    Topics: Animals; Brain; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Hypothermia; In Vitr

2003
Evidence that drugs increasing 5-hydroxytryptamine transmission block jumping but not wet dog shakes in morphine-abstinent rats: a comparison with clonidine.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:1

    Topics: Animals; Clonidine; Fenfluramine; Humans; Male; Morphine; Motor Activity; Piperazines; Rats; Rats, I

1984
Reduction in the number of serotonin receptors in the brainstem of morphine dependent rats: relation to blockade of naloxone precipitated jumping by serotonin agonists.
    Life sciences, 1980, Sep-29, Volume: 27, Issue:13

    Topics: Animals; Behavior, Animal; Brain Stem; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Na

1980
Sex differences in the discriminative stimulus effects of m-chlorophenylpiperazine and ethanol withdrawal.
    Psychopharmacology, 2000, Volume: 149, Issue:2

    Topics: Analysis of Variance; Animals; Anxiety; Central Nervous System Depressants; Discrimination Learning;

2000
Effects of trazodone and m-chlorophenylpiperazine (m-CPP) on acute dependence in mice.
    Brain research bulletin, 1991, Volume: 26, Issue:5

    Topics: Acute Disease; Animals; Behavior, Animal; Male; Mice; Morphine Dependence; Piperazines; Receptors, S

1991
The potentiation of morphine-withdrawal jumping by clonidine is antagonized by m-chlorophenylpiperazine and not by haloperidol.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Behavior, Animal; Clonidine; Dopamine Antagonists;

1986