1-(3-chlorophenyl)piperazine has been researched along with Disorder, Borderline Personality in 8 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 73 bulimic (body mass index [kg/m2] under 30, binge eating at least once weekly) and 50 normal-eater control women, we obtained indices of platelet paroxetine binding and 5-HT agonist (m-CPP)-stimulated neuroendocrine responses." | 3.72 | Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders. ( Gauvin, L; Israël, M; Kin, NM; Roussin, J; Steiger, H; Young, SN, 2004) |
| "Twelve patients with borderline personality disorder and 15 healthy comparison subjects were challenged with single doses of oral m-chlorophenylpiperazine (m-CPP) and placebo." | 2.67 | Serotonergic sensitivity in borderline personality disorder: preliminary findings. ( Cohen, L; DeCaria, CM; Hollander, E; Kellman, D; Oldham, JM; Rosnick, L; Saoud, JB; Skodol, AE; Stein, DJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paris, J | 2 |
| Zweig-Frank, H | 2 |
| Kin, NM | 2 |
| Schwartz, G | 2 |
| Steiger, H | 3 |
| Nair, NP | 1 |
| Gauvin, L | 1 |
| Israël, M | 1 |
| Young, SN | 1 |
| Roussin, J | 1 |
| Ng Ying Kin, NM | 1 |
| Vasavan Nair, NP | 1 |
| New, AS | 1 |
| Hazlett, EA | 1 |
| Buchsbaum, MS | 1 |
| Goodman, M | 1 |
| Mitelman, SA | 1 |
| Newmark, R | 1 |
| Trisdorfer, R | 1 |
| Haznedar, MM | 1 |
| Koenigsberg, HW | 1 |
| Flory, J | 1 |
| Siever, LJ | 1 |
| Hollander, E | 3 |
| Stein, DJ | 3 |
| DeCaria, CM | 2 |
| Cohen, L | 2 |
| Saoud, JB | 2 |
| Skodol, AE | 1 |
| Kellman, D | 1 |
| Rosnick, L | 1 |
| Oldham, JM | 1 |
| Simeon, D | 2 |
| DeCaria, C | 1 |
| Cohen, LJ | 1 |
| Islam, N | 1 |
| Hwang, M | 1 |
| Aronowitz, B | 1 |
| Rinne, T | 1 |
| Westenberg, HG | 1 |
| den Boer, JA | 1 |
| van den Brink, W | 1 |
4 trials available for 1-(3-chlorophenyl)piperazine and Disorder, Borderline Personality
| Article | Year |
|---|---|
Neurobiological correlates of diagnosis and underlying traits in patients with borderline personality disorder compared with normal controls.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adult; Affect; Borderline Personality Disorder; Brain; Cho | 2004 |
Serotonergic sensitivity in borderline personality disorder: preliminary findings.
Topics: Administration, Oral; Adult; Anger; Borderline Personality Disorder; Depersonalization; Fear; Female | 1994 |
Induction of depersonalization by the serotonin agonist meta-chlorophenylpiperazine.
Topics: Adult; Animals; Arousal; Borderline Personality Disorder; Brain; Depersonalization; Double-Blind Met | 1995 |
m-Chlorophenylpiperazine challenge in borderline personality disorder: relationship of neuroendocrine response, behavioral response, and clinical measures.
Topics: Adult; Behavior; Borderline Personality Disorder; Female; Humans; Hydrocortisone; Male; Neurosecreto | 1996 |
4 other studies available for 1-(3-chlorophenyl)piperazine and Disorder, Borderline Personality
| Article | Year |
|---|---|
Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders.
Topics: Adolescent; Adult; Blood Platelets; Body Mass Index; Borderline Personality Disorder; Bulimia; Child | 2004 |
Childhood sexual abuse in relation to neurobiological challenge tests in patients with borderline personality disorder and normal controls.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Borderline Personality Disorder; Child; Child Abuse, S | 2006 |
Amygdala-prefrontal disconnection in borderline personality disorder.
Topics: Adult; Aggression; Amygdala; Atrophy; Borderline Personality Disorder; Emotions; Energy Metabolism; | 2007 |
Serotonergic blunting to meta-chlorophenylpiperazine (m-CPP) highly correlates with sustained childhood abuse in impulsive and autoaggressive female borderline patients.
Topics: Adolescent; Adult; Borderline Personality Disorder; Child; Child Abuse; Child, Preschool; Female; Hu | 2000 |