1-(3-chlorophenyl)piperazine has been researched along with Chemical Dependence in 11 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Logan, BK | 1 |
| Costantino, AG | 1 |
| Rieders, EF | 1 |
| Sanders, D | 1 |
| Baron, JM | 1 |
| Griggs, DA | 1 |
| Nixon, AL | 1 |
| Long, WH | 1 |
| Flood, JG | 1 |
| Bossong, MG | 1 |
| Van Dijk, JP | 1 |
| Niesink, RJ | 1 |
| Krystal, JH | 1 |
| Webb, E | 1 |
| Cooney, N | 1 |
| Kranzler, HR | 1 |
| Charney, DS | 1 |
| Buydens-Branchey, L | 3 |
| Branchey, M | 3 |
| Fergeson, P | 3 |
| Hudson, J | 3 |
| McKernin, C | 3 |
| Tancer, ME | 1 |
| Johanson, CE | 1 |
| Moss, HB | 1 |
| Yao, JK | 1 |
| Panzak, GL | 1 |
| Lawlor, BA | 1 |
| Sunderland, T | 1 |
| Hill, JL | 1 |
| Mellow, AM | 1 |
| Molchan, SE | 1 |
| Mueller, EA | 1 |
| Jacobsen, FM | 1 |
| Murphy, DL | 1 |
| van der Laan, JW | 1 |
| Hillen, FC | 1 |
3 trials available for 1-(3-chlorophenyl)piperazine and Chemical Dependence
| Article | Year |
|---|---|
Specificity of ethanollike effects elicited by serotonergic and noradrenergic mechanisms.
Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Anxiety; Blood Pressure; Cocaine; Ethanol; Hospitalizat | 1994 |
Euphorogenic properties of the serotonergic partial agonist m-chlorophenylpiperazine in cocaine addicts.
Topics: Adult; Animals; Cocaine; Double-Blind Method; Euphoria; Humans; Piperazines; Placebos; Rats; Seroton | 1993 |
Craving for cocaine in addicted users. Role of serotonergic mechanisms.
Topics: Administration, Oral; Adult; Cocaine; Humans; Male; Piperazines; Serotonin; Serotonin Receptor Agoni | 1997 |
8 other studies available for 1-(3-chlorophenyl)piperazine and Chemical Dependence
| Article | Year |
|---|---|
Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine.
Topics: Antidepressive Agents; Cross Reactions; False Positive Reactions; Hallucinogens; Humans; Illicit Dru | 2010 |
The trazodone metabolite meta-chlorophenylpiperazine can cause false-positive urine amphetamine immunoassay results.
Topics: Amphetamine; Anti-Anxiety Agents; False Positive Reactions; Humans; Immunoassay; Piperazines; Substa | 2011 |
Methylone and mCPP, two new drugs of abuse?
Topics: Adrenergic Uptake Inhibitors; Biogenic Monoamines; Cross-Sectional Studies; Designer Drugs; Humans; | 2005 |
The meta-chlorophenylpiperazine challenge test in cocaine addicts: hormonal and psychological responses.
Topics: Adult; Anxiety; Cocaine; Humans; Hydrocortisone; Male; Piperazines; Prolactin; Serotonin Receptor Ag | 1997 |
The subjective effects of MDMA and mCPP in moderate MDMA users.
Topics: Adolescent; Adult; Affect; Analysis of Variance; Blood Pressure; Dose-Response Relationship, Drug; D | 2001 |
Serotonergic responsivity and behavioral dimensions in antisocial personality disorder with substance abuse.
Topics: Adult; Aggression; Antisocial Personality Disorder; Hostility; Humans; Hydrocortisone; Impulsive Beh | 1990 |
Evidence for a decline with age in behavioral responsivity to the serotonin agonist, m-chlorophenylpiperazine, in healthy human subjects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Arousal; Brain; Female; Humans; Hydrocortisone; Male; M | 1989 |
The potentiation of morphine-withdrawal jumping by clonidine is antagonized by m-chlorophenylpiperazine and not by haloperidol.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Behavior, Animal; Clonidine; Dopamine Antagonists; | 1986 |