1-(3-chlorophenyl)piperazine has been researched along with Binge Eating in 12 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuroendocrine, temperature, test-meal, and psychometric responses are reviewed following challenges with the post-synaptic 5-HT receptor agonist m-chlorophenylpiperazine (m-CPP), the 5-HT precursor L-tryptophan (L-TRP), and placebo in 12 patients with anorexia nervosa (AN) and 16 healthy controls." | 5.08 | Studies of serotonin function in anorexia nervosa. ( Brewerton, TD; Jimerson, DC, 1996) |
| "In 73 bulimic (body mass index [kg/m2] under 30, binge eating at least once weekly) and 50 normal-eater control women, we obtained indices of platelet paroxetine binding and 5-HT agonist (m-CPP)-stimulated neuroendocrine responses." | 3.72 | Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders. ( Gauvin, L; Israël, M; Kin, NM; Roussin, J; Steiger, H; Young, SN, 2004) |
| "We explored the impact of co-morbid avoidant personality disorder (APD), as a proxy for submissiveness, on behavioural inhibition and serotonin function in women with BN." | 1.32 | Bulimia nervosa with co-morbid avoidant personality disorder: behavioural characteristics and serotonergic function. ( Bruce, KR; Israel, M; Koerner, NM; Steiger, H; Young, SN, 2004) |
| "Although patients with severe migraine-like headaches had higher peak m-CPP levels than patients without severe headaches, these levels are not higher than other groups studied who did not get headaches." | 1.28 | Headache responses following m-chlorophenylpiperazine in bulimics and controls. ( Brandt, HA; Brewerton, TD; Jimerson, DC; Lesem, MD; Murphy, DL, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steiger, H | 6 |
| Israël, M | 6 |
| Gauvin, L | 3 |
| Ng Ying Kin, NM | 3 |
| Young, SN | 6 |
| Bruce, KR | 1 |
| Koerner, NM | 1 |
| Kin, NM | 2 |
| Roussin, J | 1 |
| Brewerton, TD | 4 |
| Murphy, DL | 3 |
| Jimerson, DC | 4 |
| Levitan, RD | 1 |
| Kaplan, AS | 1 |
| Joffe, RT | 1 |
| Levitt, AJ | 1 |
| Brown, GM | 1 |
| Kaye, WH | 1 |
| Greeno, CG | 1 |
| Moss, H | 1 |
| Fernstrom, J | 1 |
| Fernstrom, M | 1 |
| Lilenfeld, LR | 1 |
| Weltzin, TE | 1 |
| Mann, JJ | 1 |
| Koerner, N | 3 |
| Lageix, P | 1 |
| Paris, J | 2 |
| Engelberg, MJ | 1 |
| Mueller, EA | 1 |
| Lesem, MD | 2 |
| Brandt, HA | 2 |
| Quearry, B | 1 |
| George, DT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of cis9,trans11 Conjugated Linoleic Acid on Platelet Function, Markers of Haemostasis and Inflammation on Humans[NCT01234636] | 50 participants (Actual) | Interventional | 2010-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for 1-(3-chlorophenyl)piperazine and Binge Eating
| Article | Year |
|---|---|
Testmeal responses following m-chlorophenylpiperazine and L-tryptophan in bulimics and controls.
Topics: Adult; Analysis of Variance; Bulimia; Double-Blind Method; Feeding Behavior; Female; Humans; Piperaz | 1994 |
Studies of serotonin function in anorexia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Body Temperature Regulation; Body Weight; Bulimia; Double-Blind | 1996 |
Hormonal and subjective responses to intravenous meta-chlorophenylpiperazine in bulimia nervosa.
Topics: Adolescent; Adult; Affect; Bulimia; Double-Blind Method; Female; Humans; Hydrocortisone; Injections, | 1997 |
9 other studies available for 1-(3-chlorophenyl)piperazine and Binge Eating
| Article | Year |
|---|---|
Implications of compulsive and impulsive traits for serotonin status in women with bulimia nervosa.
Topics: Adolescent; Adult; Blood Platelets; Body Mass Index; Brain; Bulimia; Carrier Proteins; Compulsive Pe | 2003 |
Bulimia nervosa with co-morbid avoidant personality disorder: behavioural characteristics and serotonergic function.
Topics: Adolescent; Adult; Analysis of Variance; Bulimia; Female; Humans; Middle Aged; Personality Disorders | 2004 |
Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders.
Topics: Adolescent; Adult; Blood Platelets; Body Mass Index; Borderline Personality Disorder; Bulimia; Child | 2004 |
Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa.
Topics: Adolescent; Adult; Affect; Body Weight; Brain Chemistry; Bulimia; Feeding Behavior; Female; Follow-U | 1998 |
Implications of impulsive and affective symptoms for serotonin function in bulimia nervosa.
Topics: Adult; Affect; Binding Sites; Blood Platelets; Brain; Bulimia; Disruptive, Impulse Control, and Cond | 2001 |
Self-destructiveness and serotonin function in bulimia nervosa.
Topics: Adult; Brain; Bulimia; Female; Humans; Hydrocortisone; Piperazines; Prolactin; Receptors, Serotonin; | 2001 |
Association of serotonin and cortisol indices with childhood abuse in bulimia nervosa.
Topics: Adolescent; Adult; Blood Platelets; Bulimia; Carrier Proteins; Child; Child Abuse; Child Abuse, Sexu | 2001 |
Neuroendocrine responses to m-chlorophenylpiperazine and L-tryptophan in bulimia.
Topics: Adult; Age Factors; Body Weight; Bulimia; Circadian Rhythm; Depressive Disorder; Diagnosis, Differen | 1992 |
Headache responses following m-chlorophenylpiperazine in bulimics and controls.
Topics: Anorexia Nervosa; Bulimia; Female; Humans; Migraine Disorders; Piperazines; Reference Values | 1992 |