1-(3-chlorophenyl)piperazine has been researched along with Aggression in 12 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cocaine abuse was the most significant moderator of DeltaPRL (peak PRL-baseline PRL), and the interaction of genetic, behavioral and psychopathological measures helped predict most of the observed DeltaPRL (62." | 1.33 | Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls. ( Berrettini, WH; Gopalakrishnan, R; Hill, KP; Mannelli, P; Patkar, AA; Peindl, K; Tharwani, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klaassen, T | 1 |
| Riedel, WJ | 1 |
| van Praag, HM | 2 |
| Menheere, PP | 1 |
| Griez, E | 1 |
| Patkar, AA | 2 |
| Mannelli, P | 2 |
| Peindl, K | 2 |
| Hill, KP | 2 |
| Gopalakrishnan, R | 2 |
| Berrettini, WH | 2 |
| Tharwani, H | 1 |
| New, AS | 2 |
| Hazlett, EA | 2 |
| Buchsbaum, MS | 2 |
| Goodman, M | 2 |
| Mitelman, SA | 1 |
| Newmark, R | 1 |
| Trisdorfer, R | 1 |
| Haznedar, MM | 1 |
| Koenigsberg, HW | 1 |
| Flory, J | 1 |
| Siever, LJ | 3 |
| Hahn, RA | 1 |
| Hynes, MD | 1 |
| Fuller, RW | 1 |
| Handelsman, L | 1 |
| Holloway, K | 1 |
| Kahn, RS | 2 |
| Sturiano, C | 1 |
| Rinaldi, PJ | 1 |
| Bernstein, DP | 1 |
| Siever, L | 1 |
| Gabriel, S | 1 |
| Cooper, TB | 2 |
| Coccaro, EF | 1 |
| Kavoussi, RJ | 1 |
| Trestman, RL | 1 |
| Gabriel, SM | 1 |
| Buydens-Branchey, L | 1 |
| Branchey, M | 1 |
| Hudson, J | 1 |
| Fergeson, P | 1 |
| Cooper, RL | 1 |
| Chase, RJ | 1 |
| Tabor, J | 1 |
| Reynolds, D | 1 |
| Mitropoulou, V | 1 |
| Sprung, L | 1 |
| Shaw, RB | 1 |
| Koenigsberg, H | 1 |
| Platholi, J | 1 |
| Silverman, J | 1 |
| Wetzler, S | 1 |
| Asnis, GM | 1 |
| Korn, M | 1 |
| Moss, HB | 1 |
| Yao, JK | 1 |
| Panzak, GL | 1 |
3 trials available for 1-(3-chlorophenyl)piperazine and Aggression
| Article | Year |
|---|---|
Neuroendocrine response to meta-chlorophenylpiperazine and ipsapirone in relation to anxiety and aggression.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aggression; Anxiety Disorders; Cross-Over Stud | 2002 |
Low HDL cholesterol, aggression and altered central serotonergic activity.
Topics: Adult; Aggression; Cholesterol, HDL; Cholesterol, LDL; Cocaine-Related Disorders; Diagnosis, Dual (P | 2000 |
Serotonin receptor sensitivity and aggression.
Topics: Adult; Aggression; Anger; Anxiety Disorders; Depressive Disorder; Double-Blind Method; Female; Human | 1991 |
9 other studies available for 1-(3-chlorophenyl)piperazine and Aggression
| Article | Year |
|---|---|
Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients.
Topics: Adult; Aggression; Behavior; Cocaine-Related Disorders; Female; Humans; Inhibition, Psychological; M | 2006 |
Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls.
Topics: Adult; Aggression; Black or African American; Cocaine-Related Disorders; Disruptive, Impulse Control | 2006 |
Amygdala-prefrontal disconnection in borderline personality disorder.
Topics: Adult; Aggression; Amygdala; Atrophy; Borderline Personality Disorder; Emotions; Energy Metabolism; | 2007 |
Apomorphine-induced aggression in rats chronically treated with oral clonidine: modulation by central serotonergic mechanisms.
Topics: Aggression; Animals; Apomorphine; Brain Chemistry; Clonidine; Dose-Response Relationship, Drug; Drug | 1982 |
Hostility is associated with a low prolactin response to meta-chlorophenylpiperazine in abstinent alcoholics.
Topics: Adult; Aggression; Alcoholism; Hostility; Humans; Male; Middle Aged; Personality Disorders; Personal | 1996 |
Serotonin function in human subjects: intercorrelations among central 5-HT indices and aggressiveness.
Topics: Adult; Aggression; Depression; Female; Fenfluramine; Humans; Male; Middle Aged; Personality Disorder | 1997 |
Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment.
Topics: Aggression; Animals; Astacoidea; Behavior, Animal; Down-Regulation; Drug Administration Schedule; Dr | 2001 |
Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression.
Topics: Aggression; Fluorodeoxyglucose F18; Functional Laterality; Glucose; Gyrus Cinguli; Humans; Impulsive | 2002 |
Serotonergic responsivity and behavioral dimensions in antisocial personality disorder with substance abuse.
Topics: Adult; Aggression; Antisocial Personality Disorder; Hostility; Humans; Hydrocortisone; Impulsive Beh | 1990 |