1-(3-chlorophenyl)piperazine has been researched along with Acute Post-Traumatic Stress Disorder in 4 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven (42%) of the patients with PTSD experienced yohimbine-induced panic attacks and had significantly greater increases compared with controls in anxiety, panic, and PTSD symptoms, but not in cardiovascular measurements." | 5.08 | Noradrenergic and serotonergic function in posttraumatic stress disorder. ( Bremner, JD; Charney, DS; Heninger, GR; Johnson, DR; Krystal, JH; Morgan, CA; Nagy, LM; Nicolaou, AL; Southwick, SM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zweig-Frank, H | 1 |
| Paris, J | 2 |
| Ng Ying Kin, NM | 2 |
| Schwartz, G | 1 |
| Steiger, H | 2 |
| Vasavan Nair, NP | 1 |
| Southwick, SM | 1 |
| Krystal, JH | 1 |
| Bremner, JD | 1 |
| Morgan, CA | 1 |
| Nicolaou, AL | 1 |
| Nagy, LM | 1 |
| Johnson, DR | 1 |
| Heninger, GR | 1 |
| Charney, DS | 1 |
| Rinne, T | 1 |
| Westenberg, HG | 1 |
| den Boer, JA | 1 |
| van den Brink, W | 1 |
| Gauvin, L | 1 |
| Israël, M | 1 |
| Koerner, N | 1 |
| Young, SN | 1 |
1 trial available for 1-(3-chlorophenyl)piperazine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Noradrenergic and serotonergic function in posttraumatic stress disorder.
Topics: Adult; Double-Blind Method; Humans; Hypertension; Male; Norepinephrine; Panic Disorder; Piperazines; | 1997 |
3 other studies available for 1-(3-chlorophenyl)piperazine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Childhood sexual abuse in relation to neurobiological challenge tests in patients with borderline personality disorder and normal controls.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Borderline Personality Disorder; Child; Child Abuse, S | 2006 |
Serotonergic blunting to meta-chlorophenylpiperazine (m-CPP) highly correlates with sustained childhood abuse in impulsive and autoaggressive female borderline patients.
Topics: Adolescent; Adult; Borderline Personality Disorder; Child; Child Abuse; Child, Preschool; Female; Hu | 2000 |
Association of serotonin and cortisol indices with childhood abuse in bulimia nervosa.
Topics: Adolescent; Adult; Blood Platelets; Bulimia; Carrier Proteins; Child; Child Abuse; Child Abuse, Sexu | 2001 |